Shingles sign with stethoscope.

Valtrex and Valacyclovir Prices at CVS, Walgreens and Walmart (Updated November 2020)

Prices for Valtrex and valacyclovir were unchanged at CVS, Walgreens, and Walmart from August through November 2020. However, you could save time by ordering those drugs online from

The prices of Valtrex and valacyclovir held steady at CVS, Walgreens, and Walmart in November 2020, remaining at the same levels they reached in August. The prices for both drugs fell significantly in January at all three retailers and have remained consistently lower than the national average of $14.40 since July.

Long recognized as the treatment of choice for infections caused by the herpes simplex viruses 1 and 2, valacyclovir is a powerful antiviral drug that can also reduce the discomfort caused by shingles.

What Is Shingles?

Shingles, a viral infection characterized by a painful rash, is caused by the herpes zoster virus, which arises when the long-dormant varicella-zoster virus that causes chickenpox reactivates in adulthood.

There is no cure for any of these pesky viruses, which once contracted go into permanent residence in the host’s body. During periods of dormancy, they reside quietly in nerve cells. However, during periods of stress or immune system weakness, they can become active again, causing cold sores, genital herpes, and shingles.

How to Fight Back

Until medical science comes up with a cure for this family of herpes viruses, the best one can do is to take valacyclovir (also available under the brand name Valtrex) to minimize the number and severity of outbreaks.

Valacyclovir works by making it more difficult for herpes virus cells to multiply. This restricted ability to replicate itself lessens the frequency of herpes viral outbreaks and reduces the discomfort caused by such outbreaks as do occur.

On the price front, CVS’s price for Valtrex was unchanged at $14.34 per 500 milligram tablet in November. The Valtrex price at CVS has been $14.34 since slightly dipping in August 2020. It was previously priced at $14.38 per 500 milligram tablet.

Walgreens Much the Same

The pricing pattern at Walgreens has remained consistent since January 2020, with the exception of a slight bubble in May. Walgreens currently prices a 500 milligram tablet of Valtrex at $14.36. The price of the generic valacyclovir has remained $4.50 since January.

Following the same pricing pattern, Walmart’s price for Valtrex was $13.87 for a 500 milligram tablet throughout the period, with a slight bubble in May. The big-box store’s price for valacyclovir also held steady at $3.13 throughout the eleven-month period.

Same Pattern Emerges for Generics

Prices for valacyclovir at CVS, Walgreens, and Walmart did not vary by a penny January through November 2020. CVS’s posted price for valacyclovir was $2.86 in January and has remained the exact same through November. At Walgreens, the valacyclovir price was $4.50 in January and has not budged. Walmart priced valacyclovir at $3.13 in January and it has also remained the same through November.

These potent antiviral drugs are available at brick-and-mortar pharmacies throughout the United States and can also be ordered from reputable online prescription drug services such as Based in Tempe, Arizona, eDrugstore has been in business since the late 1990s.

Antiviral Prices at eDrugstore

The prices for Valtrex and valacyclovir at eDrugstore in November are competitive when compared to those at CVS, Walgreens, and Walmart, America’s three largest prescription drug retailers. The November prices at eDrugstore for Valtrex and valacyclovir were $17.55 and $2.67, respectively.

On top of that, eDrugstore’s prices cover not just the medications but a bundle of added-value services as well. When you order online from eDrugstore, you’ll save yourself travel to and from the local pharmacy as well as any time you might waste waiting for the pharmacist to fill your prescription. And you’ll get free delivery.

If you don’t yet have a prescription, we have a service that can help. Our complimentary consultation service will hook you up online with a physician licensed to practice in your state. If the doctor decides that you’re an appropriate candidate for the drug, a prescription will be authorized. To learn more, pay a visit to our Sexual Health page.

Randall is a medical writer with years of experience in the healthcare and pharmaceutical industries. After earning his Doctor of Pharmacy degree from the Albany College of Pharmacy and Health Sciences, he worked as an infusion and specialty pharmacist, where he discovered his passion for making trustworthy healthcare information accessible to everyone.