Shingles sign with stethoscope.

Valtrex and Valacyclovir Prices at CVS, Walgreens and Walmart (Updated June 2021)

Prices for Valtrex and valacyclovir were unchanged at CVS, Walgreens, and Walmart from August 2020 through May 2021. However, you could save time by ordering those drugs online from

The prices of Valtrex and valacyclovir held steady at CVS, Walgreens, and Walmart in May 2021, about ten cents down from the price they settled into in August 2020. The prices for both drugs fell significantly in January 2020 at all three retailers and have remained within pennies of the national average, $14.52, since July 2020.

Long recognized as the treatment of choice for infections caused by the herpes simplex viruses 1 and 2, valacyclovir is a powerful antiviral drug that can also reduce the discomfort caused by shingles.

What Is Shingles?

Shingles, a viral infection characterized by a painful rash, is caused by the herpes zoster virus, which arises when the long-dormant varicella-zoster virus that causes chickenpox reactivates in adulthood.

There is no cure for any of these pesky viruses, which once contracted go into permanent residence in the host’s body. During periods of dormancy, they reside quietly in nerve cells. However, during periods of stress or immune system weakness, they can become active again, causing cold sores, genital herpes, and shingles.

How to Fight Back

Take valacyclovir (also available under the brand name Valtrex) to minimize the number and severity of outbreaks.

Valacyclovir works by making it more difficult for herpes virus cells to multiply. This restricted ability to replicate itself lessens the frequency of herpes viral outbreaks and reduces the discomfort caused by such outbreaks as do occur.

On the price front, CVS’s price for Valtrex was unchanged at $14.34 per 500 milligram tablet in February. The Valtrex price at CVS has been $14.34 since slightly dipping in August 2020. It was previously priced at $14.38 per 500 milligram tablet. Valacyclovir is available at $2.86, the best price of the three.

Walgreens Much the Same

The pricing pattern at Walgreens has remained consistent since January 2020, with the exception of a slight bubble in May. Walgreens currently prices a 500 milligram tablet of Valtrex at $14.36. Their price for generic valacyclovir 500 milligram tablets remains at $4.50.

Following the same pricing pattern, Walmart’s price for Valtrex was $13.87 for a 500 milligram tablet throughout the period with a slight bubble in May. The big-box store’s price for valacyclovir also held steady at $3.13 through May 2021.

Same Pattern Emerges for Generics

Prices for valacyclovir at CVS, Walgreens, and Walmart did not vary by a penny January through December 2020. CVS’s posted price for valacyclovir was $2.86 in January 2020 and has remained the exact same through June 2021. At Walgreens, the valacyclovir price was $4.50 in January 2020 and has not budged to date. Walmart priced valacyclovir at $3.13 last January and it has also remained the same through June 2021.

These potent antiviral drugs are available at brick-and-mortar pharmacies throughout the United States and can also be ordered from reputable online prescription drug services such as Based in Tempe, Arizona, eDrugstore has been in business since the late 1990s.

Antiviral Prices at eDrugstore

The prices for Valtrex and valacyclovir at eDrugstore in May are competitive when compared to those at CVS, Walgreens, and Walmart, America’s three largest prescription drug retailers. The May prices at eDrugstore for Valtrex and valacyclovir have held steady at $17.55 and $2.93, respectively.

On top of that, eDrugstore’s prices cover not just the medications but a bundle of added-value services as well. When you order online from eDrugstore, you’ll save yourself travel to and from the local pharmacy as well as any time you might waste waiting for the pharmacist to fill your prescription. And you’ll get free delivery.

If you don’t yet have a prescription, we have a service that can help. Our complimentary consultation service will hook you up online with a physician licensed to practice in your state. If the doctor decides that you’re an appropriate candidate for the drug, they will authorize a prescription. To learn more, pay a visit to our sexual health page.

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