Package of Acyclovir.

Which Pharmacies Have the Lowest Prices for Acyclovir?

Acyclovir is prescribed to treat infections caused by viruses in the herpes simplex family and herpes zoster family. The lowest price for a 400-milligram tablet of the drug in October 2019 was found at, an online service. 

Acyclovir is a powerful antiviral medication that is prescribed to reduce the frequency and severity of outbreaks of genital herpes, cold sores, chickenpox, and shingles. Also sold under the brand names of Sitavig and Zovirax, acyclovir helps to relieve the discomfort of these recurrent outbreaks by inhibiting the ability of the herpes viruses to multiply within the body.

This antiviral agent is effective against infections caused by herpes simplex viruses 1 and 2, as well as the closely related herpes zoster virus, which causes chickenpox in young people and resurfaces in adults as shingles.

No Cure Has Yet Been Found

Medical science has not yet found a way to flush the herpes viruses from the body, so the best treatment for outbreaks is from antiviral medications such as acyclovir and valacyclovir (Valtrex).

These herpes family viruses take up residence in nerve cells and alternate between active phases, manifested by cold sores, genital herpes lesions, or shingles, and dormant phases when no symptoms are present. By making it more difficult for these viruses to multiply, acyclovir can significantly reduce their active phases.

How to Take Acyclovir

Acyclovir is sold in tablets of 400 milligrams, which should be taken with a glass of water at the very first sign that an active herpes infection is developing. Depending on the particular infection the patient is targeting, a 400-milligram tablet should be  taken two to five times a day. Acyclovir can be taken with or without food.

Based on an analysis of data from Secure Medical’s October 2019 review of prices for certain prescription medications, the lowest price for a 400-tablet of acyclovir was $2.09, posted at Based in Tempe, Arizona, eDrugstore is an online prescription drug service that’s been in business since the late 1990s.

Walmart Charged $5.23

The next lowest price for acyclovir was $5.23 at Walmart, the nationwide chain of superstores, all of which feature full-service pharmacy departments. A little more than a dollar more expensive was the $6.26 price for acyclovir at CVS and Target (CVS owns and operates the pharmacy departments in Target stores.)

The next lowest price — $6.34 — was found at Publix, a supermarket chain that operates in the southeastern United States. Just 11 cents higher was the $6.45 price at both Walgreens and Rite Aid. You can compare prices using the following chart.

Added-Value Services

Making the online option even more attractive is the convenience and savings in time and money that are built into prescription drug prices at eDrugstore. You won’t have to make time-consuming trips to and from the neighborhood pharmacy, and you’ll also be spared the headache of standing in line and waiting while the pharmacist fills your script.

If you don’t have a prescription for acyclovir and would find it difficult to fit a doctor’s visit into your busy schedule, eDrugstore has a convenient solution for you. Just opt for its complimentary consultation service, and you’ll be able to interact online with a licensed U.S. physician who can authorize a prescription if appropriate.

Orders placed with eDrugstore are filled promptly, packaged discreetly, and shipped free of charge to the destination you specify. Expedited shipping and handling is available for a nominal additional charge. If you’d like to learn more about eDrugstore and its services, visit its Sexual Health page.

Don Amerman has spent more than three decades in the business of writing and editing. During the last 15 years, his focus has been on freelance writing. For almost all of his writing, He has done all of his own research, both online and off, including telephone and face-to-face interviews where possible. Don Amerman on Google+