Highlights:
- Cialis (tadalafil) treats erectile dysfunction (ED), helping men achieve and maintain firmer erections.
- Known as “the weekend pill,” Cialis provides long-lasting ED treatment.
- Cialis offers unique daily dosing options, enabling spontaneous intimacy.
- Discuss with your healthcare provider to determine if Cialis is right for you.
- Common side effects include headaches and digestive discomfort. Seek immediate medical attention for serious side effects like low blood pressure or prolonged erections.
While erectile dysfunction (ED) can disrupt intimate moments, millions of men rely on Cialis to maintain a healthy sex life. With effects lasting up to 36 hours, Cialis has earned its nickname, “the weekend pill.”
It’s also available as a daily low-dose option for continuous treatment. For over two decades, Cialis and its generic version tadalafil have helped men maintain active sex lives without the need for constant planning.
What Is Cialis?
Cialis® is the brand name version of tadalafil, an ED medication developed by Eli Lilly. The FDA approved Cialis for as-needed ED treatment in 2003 and expanded approval for the daily-use version in 2008. While tadalafil provides the same effects as Cialis, the generic version typically costs significantly less.
Cialis Overview
Cialis, in both as-needed and daily formulations, belongs to a medication class called phosphodiesterase type 5 (PDE5) inhibitors. These medications enhance blood flow by relaxing blood vessels, including those in the penis.
This mechanism helps men achieve and maintain erections when sexually aroused.
Important note: Despite its long-lasting effects, Cialis does not cause erections without sexual stimulation.
What Is Cialis Used For?
Cialis/tadalafil primarily treats erectile dysfunction (ED). The condition becomes more prevalent with age and may relate to various factors including health conditions, medications, mental health, and lifestyle choices. Approximately 30 million American men experience difficulty achieving or maintaining erections.
Beyond ED treatment, Cialis serves additional medical purposes:
- Treatment of pulmonary hypertension (as Adcirca) since 2009
- Management of ED with benign prostatic hyperplasia (ED+BPH) since 2011
Effectiveness of As-Needed vs. Once-Daily Cialis
Clinical studies show Cialis and other PDE5 inhibitors effectively treat ED in 60-70% of men. While both dosing options prove effective for most men, research indicates that some men who don’t respond to as-needed dosing may benefit from switching to daily low-dose treatment.
How Does Cialis Work?
Cialis works by inhibiting the PDE5 enzyme, which helps regulate blood pressure. This action improves blood flow to the penis, supporting the physical process of achieving an erection during sexual activity. However, Cialis doesn’t affect sexual desire or cause automatic erections.
As-Needed Treatment
For occasional ED treatment or planned sexual activity within 36 hours, as-needed Cialis offers flexibility. Most men take 10 or 20 milligrams of tadalafil to achieve desired results. This extended duration enables more spontaneous intimacy.
Daily Treatment
Lower doses of 2.5 or 5 milligrams allow for continuous treatment, maintaining steady medication levels for consistent results. This option particularly benefits men with ED+BPH and may reduce side effects compared to higher doses.
Benefits of Cialis and Daily Cialis
Both dosage options of Cialis help men achieve and maintain erections for more satisfying sexual experiences.
Benefits include:
- Enhanced sexual confidence
- Improved relationship satisfaction
- Better overall intimate experiences
Does Cialis Improve Sexual Performance?
Cialis and tadalafil work by improving blood flow—they don’t increase sexual desire or ability, and they don’t directly cause an erection.
Instead, this treatment helps men achieve and maintain a firmer erection with sexual stimulation, which can lead to more satisfying sex.
Cialis vs Natural Remedies
Natural Alternatives vs. Cialis
While some natural remedies claim to treat ED, including “natural Viagra” and herbs like horny goat weed or foods like oysters, these alternatives have no supporting scientific evidence and may pose safety risks.
Cialis, Cialis for daily use, and the generic tadalafil are FDA-approved treatments specifically designed to target ED. This prescription medication is a safer, more effective way to reliably manage ED under the supervision of a medical professional.
How to Take As Needed and Daily Cialis
Cialis is available in tablet format, taken by mouth. Before you begin this or any ED medication, talk to your doctor (or one of ours) for a guide to Cialis. Make sure your healthcare provider knows about all of your chronic conditions and any other medications you take.
As Needed Cialis Dosage Instructions
The typical starting dose for as-needed Cialis is 10 milligrams, but this can be increased to 20 milligrams or reduced to 5 milligrams based on how well it works and any side effects.
Most men begin with 10 milligrams, but your doctor will determine the dose that’s right for you. Never take more than one dose in a 24-hour period, regardless of the amount.
Cialis for Daily Use Dosage Instructions
Daily Cialis comes in lower doses, usually 2.5 or 5 milligrams, to provide consistent effects over time.
This lower dose is designed to be taken at the same time every day to maintain steady levels in your body. Always follow your doctor’s instructions and don’t exceed the prescribed dose.
How to Take Cialis Pills
Swallow Cialis tablets whole with water. Unlike Viagra, splitting Cialis tablets is not recommended because of its long-lasting formula. You can take Cialis with or without food, and it won’t be affected by high-fat meals.
Best Time to Take Cialis
For as-needed Cialis, take your dose about 30 minutes to an hour before you plan to have sex.
Cialis for daily use should be taken at the same time every day, regardless of sexual activity.
How Long Does As-Needed Cialis Last?
As-needed Cialis can remain effective for up to 36 hours—perfect for romantic weekend getaways.
How Long Does Cialis for Daily Use Last?
Daily Cialis works continuously. As long as you take it every day, you can be ready for sexual activity at any time.
What Happens if I Take Too Much Cialis?
Taking too much Cialis can lead to side effects like severe headaches, dizziness, low blood pressure, and other cardiovascular issues. Seek medical attention if you experience any severe side effects.
Because Cialis lasts longer than other ED medications, there’s a higher risk that you could take too much. Always follow your doctor’s dosing instructions. Make sure you understand the benefits and side effects of your medication.
Side Effects of Cialis
Like all medications, Cialis can cause side effects. Tadalafil is not available over the counter because it could have dangerous interactions with certain medications or health conditions.
Is Cialis Safe?
For most men, Cialis is safe. In fact, some men switch from other ED medications because Cialis often has milder side effects. But because its active ingredient lasts longer in your bloodstream, certain side effects may also last longer.
You should always talk to your doctor before taking this or any other medication. Men with certain health conditions, like serious heart or liver problems, or people taking nitrates should not take Cialis.
Cialis Side Effects
Before taking an ED medication, take the time to understand the side effects of Cialis. Because Cialis is a PDE5 inhibitor, most side effects are related to changes in blood flow.
Common side effects include:
- Headache. The most common side effect of Cialis is headaches, which accounts for around 15 percent of all reported side effects.
- Upset stomach. PDE5 inhibitors have an impact on the gastrointestinal tract, so some men experience heartburn, nausea, or belching.
- Stuffy or runny nose. Because Cialis changes blood flow, taking this medication can impact the sensitive blood vessels in your sinuses.
- Back pain. Increased circulation and muscle relaxation can lead to increased sensitivity to pain—especially in the lower back.
- Flushing. Facial flushing is another common side effect of all PDE5 inhibitors. With increased blood flow throughout your body, you may experience red cheeks and a warm feeling.
Less-common side effects include:
- Dizziness. A temporary change in blood pressure can lead to dizziness or a sense of weakness.
- Temporary vision changes. These are very rare with Cialis, but some men experience blurry vision or changes in color vision. This side effect is more common (but still rare) with Viagra.
Cialis can also have serious side effects that require immediate medical attention. Rare but serious side effects can include:
- Priapism. Priapism—an erection lasting four or more hours—might sound like a joke, but it’s a serious condition that can cause damage to the penile tissue. Thankfully, it’s extraordinarily rare.
- Hypotension (low blood pressure). Cialis works by changing blood flow, and if you have existing heart conditions, this effect could lead to dangerously low blood pressure.
- Rash. Some people can experience mild itching or a rash. If you notice symptoms of an allergic reaction, call your doctor right away.
Cialis Risks and Contraindications
Some people should not take Cialis or tadalafil. Others should use it with caution or under medical supervision.
Who Should Not Take Cialis?
- People taking nitrates
- People with serious cardiovascular conditions
- People with an allergy to tadalafil or other PDE5 inhibitors
Who Should Take Cialis Only With Caution?
- People with low blood pressure
- People taking alpha-blockers
- People with liver or kidney disease
- People with active stomach ulcers
- Individuals with a history of stroke or heart attack
- People with sickle cell anemia or leukemia because these can make priapism more likely
Keep in mind that these lists are general guidelines. In special cases, doctors may feel the benefits of taking a particular medication outweigh the risks, so if you are in one of these groups, talk to your doctor about your personal situation.
Cialis Drug Interactions
Like most medications, Cialis can have drug interactions and side effects—some of which can be serious. According to Drugs.com, a significant number of drugs and supplements can interact with this medication.
The most important potential interactions to be aware of include:
- Nitrates (nitroglycerin). These cardiovascular medications work in the same way as ED medications, by relaxing blood vessels and opening blood vessels. When combined with any PDE5 inhibitor, this can lead to a sudden, dangerous drop in blood pressure.
- Alpha blockers and calcium channel blockers (doxazosin, tamsulosin, diltiazem). Taking alpha blockers and Cialis at the same time can lead to dangerously low blood pressure.
- Antibiotics (clarithromycin, erythromycin) and antifungals (itraconazole, ketoconazole). These drugs may cause Cialis and other medications to build up in your bloodstream, worsening side effects.
- Other erectile dysfunction medications (sildenafil, vardenafil, avanafil). Taking Cialis along with other ED medications can increase the risk of serious side effects like priapism and hypotension (low blood pressure).
You should not drink alcohol in excess with Cialis or tadalafil. Together, they can widen the blood vessels too much, leading to an unsafe drop in blood pressure in addition to worsened side effects like headache and dizziness.
For the complete known interactions list, visit the Drugs. Drug Interactions Checker. However, no list of potential drug interactions is complete, so let your provider know if you experience any new or unusual symptoms after taking this medication.
As-Needed Cialis and Cialis for Daily Use vs. Other ED Medications
Second only to Viagra, Cialis is one of the best-known treatments for ED—but you have even more choices. Consider your needs and speak to your doctor before deciding on the treatment that’s right for you.
Cialis vs. Viagra
Viagra (sildenafil) was the first widely accepted ED treatment on the market. Cialis and Viagra are both PDE5 inhibitors, but there are major differences:
- Duration and onset of action. Cialis kicks in after about 15 to 30 minutes, which is slightly faster than Viagra’s 30- to 60-minute onset. Viagra lasts about four to six hours, but Cialis lasts up to 36 hours—or indefinitely, when taken daily in the low-dose form.
- Dosing options. Cialis has more options—as-needed and low-dose for daily use. Viagra is only available as needed.
- Side effects. Both drugs have similar side effects like headaches, flushing, and nasal congestion. However, some men find that Cialis is easier on their stomachs. Low-dose tadalafil has fewer reported side effects than higher doses.
Cialis vs. Vardenafil
Vardenafil (previously sold under the brand name Levitra) is another powerful PDE5 inhibitor to treat ED.
- Onset and duration. Vardenafil starts working after 30 to 60 minutes and continues working for up to six hours, which is considerably shorter than Cialis.
- Strength. Vardenafil and tadalafil are both powerful, so you don’t need to take a large dose to feel the effects. However, vardenafil shouldn’t be taken daily.
- Side effects. The side effects for vardenafil and Cialis are similar and generally milder than Viagra’s. However, vardenafil has a shorter half-life, so side effects typically go away sooner than with long-acting Cialis.
Cialis vs. Stendra
Stendra (avanafil) is a newer generation PDE5 inhibitor with promising, rapid results for treating ED.
- Onset and duration. Stendra can start working after just 15 minutes and can last up to six hours. That’s about the same as Cialis, but again, Cialis has a much longer duration.
- Generic options and cost. Cialis and Cialis for daily use are also available as the generic tadalafil, but currently, Stendra is only available by brand name and is more expensive.
- Side effects. Stendra has a more selective action on the PDE5 enzyme, so it may have fewer side effects than Cialis and other ED treatments.
What Is the Best ED Medication?
Cialis, Viagra, vardenafil, and Stendra are all in the same drug class and work in approximately the same way. Your doctor will help you find the right treatment or the best Cialis alternative that has manageable side effects and relieves your ED.
Cialis Pricing and Availability
The cost and availability of Cialis varies depending on where you shop, whether you choose brand-name or generic, and whether your insurance will help cover the cost.
Cialis vs Tadalafil Cost
If price is your main concern, you’ll probably prefer the generic form, tadalafil.
Across all pharmacies, brand-name as-needed Cialis currently costs around $60 per tablet for 20 milligrams. Cialis for daily use costs a little more than $13 per tablet for 5 milligrams. Tadalafil costs an average of $6.78 for 20 milligrams and $2.10 for 5 milligrams.
Is Cialis Covered by Insurance?
When used to treat erectile dysfunction with no other medical need, Cialis is probably not covered by your insurance. If you need tadalafil for benign prostate hyperplasia or pulmonary hypertension, however, your insurance probably will cover your prescriptions.
Always check with your insurance provider for coverage details.
Where Can I Find Cialis Discounts?
eDrugstore offers great deals for 50 or even 75 percent off on select products each month. Shop in bulk for extra savings and discounts—and always free delivery.
Is It Safe to Buy Cialis Online?
Yes! Always choose a reputable online source, like eDrugstore, to buy ED meds online. Remember, Cialis is by prescription only, so only shop with licensed pharmacies that require a valid prescription.
Watch out for other common mistakes so you can shop safely and make sure you’re always getting FDA-approved, genuine medications.
The Advantages of Buying Cialis and Cialis for Daily Use Online from eDrugstore
With eDrugstore, delivery of Cialis or Cialis for daily use is just a few clicks away. It’s an easy, discreet, and safe way to manage your ED without the hassle of a doctor’s visit.
- Easy and convenient. You don’t need an appointment to get your medication from eDrugstore. Our U.S. licensed pharmacists will check your health and help you find the right medication for you.
- Guaranteed quality. You’ll only find FDA-approved, genuine medications at eDrugstore.
- Cost savings. Get a free medical consultation, free shipping, and special discounts up to 75 percent off with eDrugstore. Be sure to check for bulk buying options to save on Cialis for daily use.
- Complete privacy. Your order ships in fast, discreet packaging to keep your order private, and we’ll never share or sell your personal information.
- 24/7 support. Have questions? eDrugstore’s licensed pharmacists are always available to assist you.
Be Ready for Anything with Cialis
Cialis is the longest-lasting erectile dysfunction drug on the market, and it’s the only one that’s available in a low daily dose. If you’re wondering whether it’s right for you, eDrugstore offers a free medical consultation with a licensed U.S. physician to help you decide.
You can order with confidence from eDrugstore, where it’s always safe to buy Cialis, Cialis for daily use, or tadalafil online.
Disclaimer: This article provides general information about health and related topics but is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
