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How to Take Cialis and Get the Best Results

Cialis and its generic equivalent, tadalafil, are the longest lasting erectile dysfunction medications on the market. Their versatility and popularity can be chalked up to their extraordinarily lengthy half-lives.

More than a decade and a half after its 2003 introduction, Cialis remain a powerful force in the U.S. erectile dysfunction drug market. It was second only to Viagra in terms of sales from late 2018 into very early 2019.

Along with tadalafil, its generic equivalent, Cialis accounted for 30 percent of all ED drug prescriptions filled between December 1, 2018, and January 31, 2019, according to a report posted at CNBC.com. During that same period, Viagra and its generic equivalent, sildenafil citrate, captured 65 percent of the ED drug market. The remaining 5 percent was carved up by Levitra, Staxyn, Stendra, and the generic equivalents of Levitra and Staxyn.

Two Formulations

Cialis is the only ED drug that’s available in two formulations -- one for daily use and the other for use on demand. Both have the identical active ingredient. The only difference between the two is in the strength of the dosage. Daily Cialis is marketed in tablets of 2.5 and 5 milligrams, while the on-demand version of the drug is available in tablets of 10 and 20 milligrams.

An extraordinarily lengthy half-life accounts for the amazing versatility of Cialis and tadalafil. Half-life is the time it takes for the concentration of the drug circulating in your bloodstream to be reduced by half. The half-life of Cialis is 17.5 hours, significantly higher than any other ED medication.

Taking Cialis (Tadalafil) on Demand The recommended starting dose of Cialis on demand is 10 milligrams, which can be adjusted upward to 20 milligrams if the lower dosage isn’t sufficient to get the job done.

The erection-friendly effects of Cialis on demand can last for up to 36 hours, which has earned it the nickname of the “weekender pill.” The effects of a 10-milligram Cialis tablet taken at 9 p.m. on a Friday probably won’t wear off completely until about 9 a.m. on Sunday.

Most Cialis users report that they notice the drug becoming effective about 30 minutes after it’s taken. However, it can take up to two hours for the drug’s active ingredient to reach maximum concentration in the bloodstream.

Taking Daily Cialis (Tadalafil)

Designed for men who would like to be ready for sex whenever the opportunity arises, daily Cialis must be taken once a day, preferably at the same time of day. It will take three or four days for the concentration of the drug to reach sufficient levels to ensure you’ll be able to get and keep an erection whenever the time is right.

As previously noted, daily Cialis is available in tablets of 2.5 and 5 milligrams. The recommended starting dose for daily Cialis is 5 milligrams, which can be adjusted downward to 2.5 milligrams if the lower dose is enough to produce the desired results.

Can I Take Cialis with Food?

No matter which formulation of Cialis you choose, the medication can be taken with or without food. It is possible that a pill taken shortly after the consumption of a heavy or very fatty meal might take a bit longer to become effective, but the food itself should not interfere with the workings of the medication. However, avoid grapefruit juice when taking Cialis, because it tends to potentiate the blood pressure-lowering effects of the drug.

It’s also probably best to minimize alcohol consumption around the time you plan to take Cialis or tadalafil. To temporarily boost blood flow to the penis, the drugs lower central blood pressure. Alcohol has the same effect on blood pressure, so it’s wise to moderate alcohol consumption when using the ED drug.

Interaction with Other Drugs

Cialis (tadalafil) isn’t appropriate for men taking nitrate-based medications, which also sharply lower blood pressure. Taken at or about the same time, the effects of these two drugs could conceivably trigger a life-threatening drop in blood pressure. This warning also applies to the recreational drugs known as “poppers,” which also contain nitrates and thus are off limits when using Cialis or any other ED drug for that matter.

Multiple clinical trials have shown Cialis to be safe and effective for the vast majority of men. However, if your doctor has instructed you to avoid sexual activity -- either temporarily or long-term -- because you’re still recovering from a heart attack or are suffering from advanced stages of heart failure, do as your doctor directs.

Side Effects of Cialis (Tadalafil)

The use of Cialis or tadalafil can trigger a number of common side effects, although these generally are mild and tend to dissipate upon continued use. Such side effects include back pain, diarrhea, dizziness, facial flushing, headache, indigestion, muscle ache, nausea, and a runny or stuffy nose.

Although very rare, more serious side effects of Cialis include priapism, an erection that lasts for four hours or more, and a sudden decrease or loss of hearing or vision. Should you experience any of these adverse effects, seek medical attention immediately.

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Whether you choose Cialis or its generic equivalent, tadalafil, you may find that you can save both time and money by ordering online from eDrugstore.com, a longtime online facilitator. Based in Tempe, Arizona, eDrugstore supplies a full range of ED medications, both brand-name and generic. To learn more, visit its Erectile Dysfunction page.

By Don Amerman