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More than 18 years after it first became available in the United States, Viagra remains one of the nation’s top-selling drugs for the treatment of erectile dysfunction. In less than two decades, Pfizer’s groundbreaking drug has dramatically altered the treatment of ED in this country and around the world. It has also paved the way for the introduction of a handful of similar impotence medications.
For at least another year, Viagra is protected from generic competition in this country. Actually, Pfizer’s U.S. patent on the little blue pill doesn’t expire until April 2020, but the drugmaker struck an agreement in 2013 that could permit generic competition as early as December 2017. Under Pfizer’s accord with Israeli pharmaceuticals giant, Teva, the latter could begin to market a generic formulation of Viagra late next year. However, because Pfizer’s patent is valid until 2020, Teva would be required to pay the American drugmaker a royalty for the privilege of manufacturing and marketing a generic version of the drug.
Available Only by Prescription
In the meantime, Viagra is available only by prescription and can be purchased at your local neighborhood pharmacy or online from a handful of reliable Internet drugstores that sell only FDA-approved drugs sourced from licensed U.S. pharmacies. One such supplier is eDrugstore, part of the Secure Medical family of online drugstores. For men who do not have a prescription for Viagra or another such drug, eDrugstore can set up a complimentary consultation with one of its team of licensed U.S. physicians. If you already have a prescription from your doctor, you can fax or scan and email it along with your order.
The average price of a 50-milligram dose (the recommended starting dose) of Viagra from eDrugstore is $30.75. To get that price, you’ll have to order five to nine 100-milligram Viagra tablets, which will yield 10 to 18 50-milligram doses when cut in half with the complimentary pill-splitter eDrugstore includes with every first order. eDrugstore’s price for five 100-milligram Viagra tablets is $307.50. It increases by $61.50 per 100-milligram tablet to a total of $553.50 for nine 100-milligram pills. Buy more than nine tablets, and the price per dose drops even further.
Buy More, Save More
If you’ve used Viagra in the past and found that it works well for you, an order of five to nine 100-milligram tablets — or even more — makes good sense financially. If you have not yet used Viagra and would like to give it a try, you should start with a smaller order — one or two 100-milligram tablets — so that you can determine if it produces the desired results for you without any notable side effects. Once you’ve made that determination, you can increase the size of subsequent orders to save more per dose.
An order of only one 100-milligram Viagra tablet, yielding two 50-milligram doses, will cost you $75.00, or $37.50 per 50-milligram dose. Two 100-milligram tablets, which will yield four 50-milligram doses, are priced at $134, or $33.50 per dose.
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For most men, the recommended starting dose of 50 milligrams is sufficient to produce the desired results, namely an erection firm and long-lasting enough for sexual intercourse. A few may find that they need an entire 100-milligram tablet to produce comparable effects and thus will have to pay more per dose.
It All Started with Viagra
As previously noted, Viagra was the first of a new wave of oral erectile dysfunction medications to be marketed in the United States and elsewhere. It was the first of a family of medications known collectively as PDE5 inhibitors, so called for their ability to temporarily deactivate an enzyme known as phosphodiesterase-5, which can interfere with robust blood flow to the penis.
The vast majority of erectile dysfunction is caused by insufficient blood flow to the penis, which can be traced to atherosclerosis, the buildup of fatty plaque on artery walls, and a number of other physiological ills. It’s estimated that 10 to 20 percent of ED is psychological in origin, and Viagra and the other PDE5 inhibitors are unlikely to overcome impotence of this type.
Erections Start in the Brain
Erections begin in the brain and not in the penis. When the body’s nerve center detects feelings of sexual desire or physical stimuli to a man’s erogenous zones, it releases a flood of nitric oxide that courses toward the pelvic region. The nitric oxide triggers secondary chemical reactions, one of which gives rise to a substance known as cyclic guanosine monophosphate, or cGMP. As blood levels of cGMP rise, the smooth muscles lining the arteries that feed the penis relax, increasing the volume of blood they can carry. This rush of blood into the penis quickly fills the spongy erectile tissue of the penis, creating an erection.
One of the primary tasks of the PDE5 enzyme is to break down cGMP. This is of little concern in men with robust vascular health, because more cGMP arises to take its place. In those whose blood flow is already below par, the PDE5 enzyme can quickly wipe out the cGMP and thus sabotage erectile function.
How PDE5 Inhibitors Work
Viagra and the other PDE5 inhibitors hold the PDE5 enzyme at bay for four or more hours, which gives a man time to achieve and maintain an erection strong enough for sexual activity. It is not a cure for ED, but it does allow a man to temporarily overcome the effects of ED so that he can enjoy an active sex life.
Viagra has a few side effects, most of them mild and most of which disappear upon continued use. These include back and muscle pain, dizziness, headache, nausea, runny or stuffy nose, and upset stomach. More serious side effects, which are rare, can include a sudden loss of vision or hearing and an erection that lasts for more than four hours. In the unlikely event you should experience one of these more serious side effects, seek medical attention immediately.
If you would like to place an order for Viagra or another popular ED drug or would like to learn more about erectile dysfunction and its treatment, pay a visit to our Erectile Dysfunction Page.
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