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Curious about how Viagra works on your body? Here’s a minute-by-minute account of the little blue pill’s effects.
According to a study published in the British Journal of Clinical Pharmacology, some men feel the effects of Viagra quite rapidly, achieving an erection in just 12 minutes. But according to the study, the average time from taking a 50 mg dosage to getting an erection is 27 minutes.
During these first 12 to 27 minutes (depending on the man), Viagra binds to the PDE5 enzymes that break down cGMP, rending the enzymes useless. With cGMP freely available to increase blood to the penis, an erection occurs.
It’s important to note that simply taking Viagra won’t give you an erection; you must be sexually stimulated for Viagra to make you hard.
Peak Performance
If you take Viagra on an empty stomach, it reaches its highest blood concentration in about an hour. Taking it with food can reduce Viagra’s concentration in the blood by nearly one-third.
Here’s a brief rundown of how long an average erection lasts after time passes, according to a study in The Journal of Sexual Medicine.
- After 1 hour, erections lasted 33 minutes.
- After 8 hours, erections lasted 23 minutes.
- After 12 hours, erections lasted 16 minutes.
(For men taking a placebo, erections lasted 7 minutes.)
The Day After
About 24 hours after you take Viagra, it’ll be out of your system. As for the warnings, there are a few:
- Don’t take more than one dose of Viagra within 24 hours.
- If you have a continuous erection lasting more than four hours, contact your doctor. This is not the same thing as achieving multiple erections within four hours.
- Do not take Viagra if you take nitrates.
- Do not take Viagra if you are using a GC stimulator, such as riociguat.
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