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For some men, supplementing Cialis with testosterone is necessary to fight erectile dysfunction. Although there are certainly some good side effects of testosterone, such as more energy or a greater ability to build muscle, it does have some potential negative side effects.
Shrinking testicles
According to Men’s Health, shrinking testicles is one of the most common side effects of testosterone replacement therapy.
Why does it happen?
While you might imagine testosterone helping you to grow some “big balls,” the truth is that there’s a chemical reaction that makes them smaller. When you get extra testosterone put into the body, your pituitary gland will think there’s plenty, so it will stop supplying luteinizing hormone (to tell your testicles to produce more testosterone) and follicle stimulating hormone (to get your body to produce sperm).
Since your testicles think they don’t need to produce sperm, they start shrinking. No big deal if you don’t plan to have any more kids. But don’t assume it can be reversed, as long-term testosterone therapy may reduce your chances of getting back to a normal sperm production rate.
Swollen feet and ankles
The hormones raging through pregnant women aren’t the only ones that can make feet and ankles swell.
Testosterone causes your body to retain fluid, especially if you’re getting a big dose in one session (vs. reduced dosages in daily treatments).
Enlarged breasts
Known as gynecomastia, testosterone-induced breast enlargement is a rarer side effect but it does happen.
Testosterone converts some of the hormone into estradiol, a form of estrogen. If you’ve already got more breast tissue than most men, the testosterone supplement could trigger the growth of breast tissue. But again, it’s quite rare.

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