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Today we’re going to talk about some of the steps you can take to ensure that your ED medications are as safe as possible.
In general, PDE5 inhibitors like Viagra, Cialis, and Levitra are extremely safe drugs. One of the only things that patients need to watch out for are complications that arise from other drugs.
But this fact is important to be mindful of, considering that many patients with ED are on other medications.
The Basics
All PDE5 inhibitors belong to a class of drug called vasodilators, which means that these drugs expand the blood vessels in a person’s body, allowing more oxygen and nutrients to reach cells, as well as enhancing blood flow to the penis, causing an erection.
Vasodilators can be a source of interactions with ED medications, and if you’re on medication for high blood pressure or coronary heart disease, make sure to talk to your doctor before using Viagra, Cialis, or Levitra.
- Common vasodilators include nitrates and alpha-blockers, such as Cardura, Minipress, Hytrin, Flomax, and Uroxatral.
Although there can be interaction between other drugs that are vasodilators, other complications arise from mixing with other drugs that affect levels of the enzyme CYP3A4, which is the most important enzyme for metabolizing erectile dysfunction medicine.
Drugs that inhibit CYP3A4 activity will stop ED medication from being metabolized. This effect can dramatically increase the levels of erectile dysfunction medication in the bloodstream, which can then potentially reach toxic levels.
- Space constraints limit our ability to post atable of CYP3A4 inhibitors, so make sure to tell your doctor exactly what medications you’re taking, and that applies if you’re getting your prescription through our online evaluation as well!
- Also, keep in mind that grapefruit juice is an unusual case that also inhibits CYP3A4 activity.
Drugs the increase CYP3A4 activity are not dangerous, but they may prevent erectile 
dysfunction medication from being effective.
- Some antibiotics, such as Rifampin, will decrease CYP3A4 activity. St. John’s Wort, another inhibitor, might also reduce the effectiveness of ED medications.
Conclusion
Here at eDrugstore, we’re one-hundred percent committed to making sure your sex life is vital and enjoyable.
So as part of that mission, we want you to get the most of your erectile dysfunction medication, and use it with safety!
More than anything else, we’d like to hear what your questions and concerns are when ordering ED medication online, or even what you’re curious about concerning lifestyle medications in general!
So leave a comment below, tell us a bit about how our products have improved your life, or ask any question that comes to mind.
We specialize in providing our over 1,000,000 customers with relevant product and condition information created by our professional editorial staff which includes our team of medical writers, medical practitioners, and health educators. eDrugStore.com Staff on Facebook