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Each with its own unique characteristics, Cialis and Staxyn offer a stark choice for men with ED. It depends on their needs and the frequency of sexual activity which of the two best suits their needs.
Cialis and Staxyn are two prescription drugs that are used to treat erectile dysfunction (ED). Cialis has been on the market since 2003, and Staxyn has been available since 2010. However, the active ingredient in Staxyn, Vardenafil, is also the active ingredient in Levitra, which gained FDA approval in 2003. The difference between Staxyn and Levitra is that Staxyn is an orally disintegrating tablet, while Levitra is a tablet that must be swallowed with a liquid.
How Does Cialis Work?
The active ingredient in Cialis is tadalafil, and it is a PDE5 inhibitor. Phosphodiesterase-5 is an enzyme found in the smooth muscle cells lining blood vessels of the penis, and it breaks down a compound known as cyclic guanosine monophosphate, or cGMP. Without adequate levels of cGMP, it is difficult to achieve an erection. Tadalafil binds to PDE5, so that it can’t break down cGMP. With more circulating cGMP, it is easier to achieve an erection in the presence of sexual stimulation.
Cialis is available to buy in dosages of 2.5, 5, 10, and 20 milligrams, and is the only ED medication that may be taken as a once-daily medication. Unlike Viagra, Levitra, and Staxyn, which have effects lasting four to six hours, high-dose Cialis may be effective for up to 36 hours.
How Does Staxyn Work?
Staxyn’s active ingredient, vardenafil, is also a PDE5 inhibitor, but it is chemically slightly different than tadalafil and sildenafil citrate, the active ingredient in Viagra. Staxyn dissolves under the tongue, and because the area under the tongue is rich in blood vessels, the drug enters the system more rapidly than a pill that must be swallowed and broken down in the digestive system. Staxyn is effective for slightly longer than Viagra in most men, but it is not effective for as long as Cialis.
Side Effects of Cialis and Staxyn
With Cialis, the most common side effects are headache, upset stomach, back or muscular pain, facial flushing, and stuffy nose. Back and muscular aches tend to occur 12 to 24 hours after taking Cialis, while other side effects tend to happen shortly after taking the drug. Men who take nitrates for heart problems should not take their nitrate drugs within 48 hours of taking Cialis, due to the potential for a sudden drop in blood pressure that could be dangerous. Recreational drugs like amyl nitrite should be avoided for the same reason.
Side effects with Staxyn are similar to those with Cialis. In rare cases, Staxyn can result in a painful, prolonged erection that can cause permanent tissue damage if not treated promptly. Like Cialis, Staxyn should not be taken with nitrates. Men who take nitrates for heart problems should not take ED drugs except under the strict supervision of a physician.
How Their Costs Compare
Costs are comparable between Cialis and Staxyn, though Cialis is slightly more expensive. Expect to pay about $48 per 10-milligram dose of Cialis (derived by splitting a 20-milligram tablet in two), compared to $40 per 10-milligram dose of Staxyn. Tadalafil, the generic equivalent of Cialis, costs about $29 per 10-milligram dose (derived by dividing a 20-milligram tablet in two). Staxyn is not yet available in generic form. None of these drugs should be taken more than once a day.
What Men Prefer About Cialis
The main thing men like about high-dose Cialis (10- to 20-milligram tablets) is that it works for up to 36 hours, compared with four to six hours for most other ED drugs. Anecdotal reports indicate that some men find Cialis to have a less pronounced effect, which is outweighed by the longevity of the drug’s effectiveness and generally milder side effects. The fact that it can be taken at a low dose as a once-daily medication makes it more convenient for sexual spontaneity than other ED drugs which must be taken half an hour to an hour before sexual activity. Cialis has earned the nickname “The Weekender” because it can be taken on a Friday evening and remain effective for most of the weekend.
What Men Prefer About Staxyn
With Staxyn, men prefer the convenience of being able to take the drug without water. Staxyn is also packaged very discreetly in a small, black container that easily fits in a pocket and looks like a pack of gum. It is far more convenient to remove a Staxyn tablet and place it under the tongue than to carry a bottle of Viagra, Cialis, or Levitra and take it with water. Though users of Staxyn are instructed to take the drug half an hour before sexual activity, many men report that the drug takes effect in 15 to 20 minutes.
The following table sums up the differences and similarities between Cialis and Staxyn.
| Cialis | Staxyn | |
| Active ingredient name | Tadalafil | Vardenafil |
| Duration of effects | Up to 36 hours | About 5 hours |
| Available dosages | 5mg, 10mg, 20mg | 10mg orally disintegrating tablets |
| Interaction with food | May be taken with food | May be taken with food |
| When to take | 30 minutes before sexual activity | 30 minutes before sexual activity |
| Most common side effect | Headache, indigestion, stuffy nose. Delayed muscle ache, in some cases. Anecdotal evidence suggests side effects are milder with Cialis than with Viagra. | Headache, indigestion, stuffy nose. Delayed muscle ache, in some cases. |
| Typical cost per dose | $29 to $48 | $39 to $40 |
| Main selling point | Effects can last up to 36 hours; hence the nickname “the weekend pill.” May allow greater sexual spontaneity. | Sleek packaging makes it less of a hassle to carry around. Does not have to be taken with water and does not have to be taken on an empty stomach. |
Obtaining Cialis and Staxyn Safely
Like any other prescription drug, Cialis and Staxyn may be prescribed by your family physician and filled at your local drugstore. However, for obvious reasons, many men are hesitant to bring up the topic of ED with their family physician. Another option for obtaining Cialis, generic tadalafil, and Staxyn is to work with an online facilitator such as eDrugstore.com.
In business since the late 1990s, Arizona-based eDrugstore can set up a complimentary online consultation with a licensed U.S. physician who can authorize a prescription if appropriate. Men who don’t already have a doctor’s prescription can save time and money by availing themselves of this service. To learn more, visit eDrugstore’s Erection Problems page.
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