| Pharmacy | Acyclovir 400mg |
|---|---|
| CVS / Target |
$20.69 $0.69/day
|
| Walgreens |
$20.45 $0.68/day
|
| Walmart |
$13.37 $0.45/day
|
| Costco |
$18.98 $0.32/day
|
| Amazon |
$9.72 $0.32/day
|
| Average Price |
$16.64 $1.66/day
|
†Quantity and pack size vary by retailer. Per-day price = price ÷ days' supply.
This month, CVS / Target charges $0.69 per dose for acyclovir 400 milligrams, generic Zovirax, at the most commonly prescribed strength.
Acyclovir is typically taken more often than newer antivirals like valacyclovir, often three to five times a day depending on what’s being treated. That schedule affects how much a full course actually costs, even when the per-pill price looks low.
Prices like these shift from month to month based on manufacturer contracts, insurance negotiations, and how many generic competitors are actively selling in the market.
eDrugstore carries generic acyclovir, not the brand-name Zovirax; the generic version works identically at a lower cost. Ready to get started? Order acyclovir today and skip the pharmacy counter.
Acyclovir was approved by the FDA in the early 1980s under the brand name Zovirax, making it one of the oldest antiviral medications still in common use. Generic acyclovir, chemically identical to Zovirax, is now the version most commonly prescribed. It’s used to manage outbreaks of genital herpes, cold sores, shingles, and chickenpox.
Acyclovir doesn’t cure the herpes virus. It works by interfering with the virus’s ability to replicate its DNA, which shortens outbreaks and reduces how severe symptoms are. Because it clears the body faster than newer antivirals, it’s usually dosed several times a day rather than once or twice.
If you have reduced kidney function, tell your provider before starting acyclovir. Your dose may need to be adjusted, and staying well hydrated while taking it can help reduce the risk of kidney-related side effects.
For more information about dosing, timing, and what to expect, read our Acyclovir FAQs.
Every pharmacy on this list requires a valid prescription before dispensing acyclovir (generic Zovirax). eDrugstore simplifies the process by offering an online consultation with a U.S.-licensed physician, who can issue a prescription when appropriate. Once approved, eDrugstore handles fulfillment and ships your order.