Cialis and Tadalafil Prices at Walmart

Update for July 2026

*Based on 20 mg pill split in half

Cialis Prices

This month’s prices at Walmart for Cialis are same as last month. with the exception of Cialis 5 milligram, which has dropped from $12.91 last month to $10.57. The 20 milligram price is $59.04, and for those who split their pills, the cost of a 10 milligram dose — the recommended starting dose — is once again $29.52.

Tadalafil Prices

Tadalafil prices at Walmart are also exactly the same as last month: Tadalafil 5 milligrams is $1.38. The 10 milligram tablet will cost you $1.09 and the 20 milligram dose $2.19. 

About Cialis and Tadalafil 

Cialis is a brand name for tadalafil, a phosphodiesterase-5 (PDE-5) inhibitor that relaxes smooth muscles, thereby increasing the blood flow to the penis and facilitating erections. 

Cialis’ effects last longer than Viagra’s. Tadalafil supports erections for up to 36 hours, while sildenafil, the active compound in Viagra, boosts erectile function for four to six hours. 

The longer effectiveness of Cialis comes at a price. Men who want to be ready for 36 hours have to be ready to pay more for the privilege. Both compounds may cause side effects like light-headedness, nasal congestion, and headaches. Given that its effects last longer, Cialis’ side effects may last longer as well. 

Doctors advise their patients to take one Cialis or generic tadalafil pill per day orally, with or without food.

Indications: What Cialis and Tadalafil are Used For

Tadalafil’s primary use as Cialis is to treat erectile dysfunction. It can also alleviate the symptoms of benign prostate hyperplasia (BPH), making it easier for sufferers to urinate and empty their bladders. 

Under different brand names, tadalafil also treats the symptoms of pulmonary arterial hypertension (PAH), allowing patients to overcome dizziness, tiredness, and shortness of breath. By relaxing the smooth muscles, tadalafil relieves high blood pressure in the arteries carrying blood to the lungs. 

How do PDE-5 Inhibitors Work?

PDE-5s are enzymes in the blood vessel walls that control blood flow and cell signaling in the body. Specifically, they control the breakdown of the nucleotides cAMP and cGMP into their inactive versions. These nucleotides are like messengers in intercellular communication. 

The role of PDE-5s is essential, and they are present in tissues all over the body. But sometimes, their activity may result in unwanted side effects like erectile dysfunction and high blood pressure.   

PDE-5 inhibitors counter the action of these enzymes. By blocking PDE-5, these compounds relax blood vessels and increase blood flow. 

In addition to treating erectile dysfunction and pulmonary arterial hypertension, PDE-5 inhibitors can lower blood pressure and may help with cardiovascular diseases and cancer.

Contraindications: Who Should Not Take Cialis and Tadalafil

Patients who take nitroglycerin tablets or use patches should not take Cialis or generic tadalafil. Nitrates combine with tadalafil to cause extreme drops in blood pressure. In some cases, extremely low blood pressure can be fatal. 

Men with heart muscle enlargement or a condition known as left ventricular outlet obstruction should not take tadalafil. In their case, the medication may cause side effects, including light-headedness and fainting. 

Don’t use Cialis or tadalafil if you suffer from any of the following conditions: 

• Recent stroke or heart attack
• Heart failure
• Heart pains
• Irregular heartbeat
• Problems with your retina
• Severe liver disease 

According to the FDA, no one has studied tadalafil’s effects on these conditions. 

In rare cases, tadalafil and other PDE-5 inhibitors may cause a prolonged erection (priapism). Priapism is a serious condition requiring immediate medical attention. If you have an erection that lasts more than four hours, seek medical assistance immediately. 

Cialis and Tadalafil Risks and Side Effects

• Dizziness
• Flushing
• Stuffy nose
• Back pain
• Headache
• Upset stomach
• Fainting
• Light-headedness
• Nausea 

Some of the more extreme but rare side effects include: 

• Impaired vision
• Permanent blindness in one or both eyes
• Impaired hearing
• Priapism (prolonged and painful erection)
• Allergic reactions like a rash, trouble breathing, swelling of the tongue or throat 

Although these extreme side effects are rare, you should be aware that you are more likely to develop them if you have high cholesterol, heart disease, or high blood pressure.

Special Considerations for Cialis and Tadalafil

The combination of tadalafil and nitrates can lead to extremely low blood pressure that might be fatal. 

Using Cialis with an alpha-blocker like tamsulosin can also lower blood pressure. 

Some antibiotics, antifungals like ketoconazole, HIV drugs like ritonavir, and hepatitis C drugs can affect the tadalafil’s elimination from the body and thus its effects.

What You Get for Your Prescription Dollars

How long does it take to get a script filled at a brick-and-mortar retail pharmacy? An hour, if we’re being generous? Plus, another hour of driving between the pharmacy and your home? And if your doctor forgets to call the prescription in — forget it. All of it is wasted time that costs you money.

How much money?

Well, how much do you make per hour at your job? Multiply that by how much time you’ll spend filling your prescription, and you’ll get the amount you would save by ordering from eDrugstore instead.

That’s because we aren’t just another online pharmacy; we’re also a full-service health facilitator who can connect you to a licensed physician who can evaluate your erectile dysfunction and write your prescription.

Whether you use one of our doctors or your own, we’ll ship your medication discreetly to your door for no extra cost.Save time while preserving your peace of mind. Check out our selection of medications for erectile dysfunction and sexual health today.