Results from a study conducted from 1996-2004 have been released, which show that HIV-infected women who smoke crack cocaine are speeding up the effects of the virus. This research studied 1,686 women with HIV, and 29 percent of those women smoked crack during the study. The study found that women with HIV who consistently smoked crack were more than three times as likely to die from AIDS-related causes than those women who did not smoke the drug. Even those participants undergoing antiretroviral therapy to treat their HIV infection experienced increased immune system deterioration as a result of their crack cocaine drug use. The study also found that those who only intermittently used crack also had a greater immune function decline.

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