{"id":39364,"date":"2024-12-12T03:24:11","date_gmt":"2024-12-11T20:24:11","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=39364"},"modified":"2025-09-05T20:54:40","modified_gmt":"2025-09-05T13:54:40","slug":"guide-to-cialis","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/guide-to-cialis\/","title":{"rendered":"The Ultimate Guide to Cialis and Tadalafil"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Highlights:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Cialis (tadalafil) treats erectile dysfunction (ED), helping men achieve and maintain firmer erections.<\/strong><\/li>\n\n\n\n<li><strong>Known as &#8220;the weekend pill,&#8221; Cialis provides long-lasting ED treatment.<\/strong><\/li>\n\n\n\n<li><strong>Cialis offers unique daily dosing options, enabling spontaneous intimacy.<\/strong><\/li>\n\n\n\n<li><strong>Discuss with your healthcare provider to determine if Cialis is right for you.<\/strong><\/li>\n\n\n\n<li><strong>Common side effects include headaches and digestive discomfort. Seek immediate medical attention for serious side effects like low blood pressure or prolonged erections.<\/strong><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">While erectile dysfunction (ED) can disrupt intimate moments, millions of men rely on Cialis to maintain a healthy sex life. With effects lasting up to 36 hours, Cialis has earned its nickname, &#8220;the weekend pill.&#8221;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It&#8217;s also available as a daily low-dose option for continuous treatment. For over two decades, Cialis and its generic version tadalafil have helped men maintain active sex lives without the need for constant planning.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What Is Cialis?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis\u00ae is the brand name version of tadalafil, an ED medication developed by Eli Lilly. <a href=\"https:\/\/investor.lilly.com\/news-releases\/news-release-details\/cialisr-tadalafil-marks-10-years-us-approval\">The FDA approved Cialis<\/a> for as-needed ED treatment in 2003 and expanded approval for the daily-use version in 2008. While tadalafil provides the same effects as Cialis, the generic version typically costs significantly less.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis Overview<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis, in both as-needed and daily formulations, belongs to a medication class called phosphodiesterase type 5 (PDE5) inhibitors. These medications enhance blood flow by relaxing blood vessels, including those in the penis.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This mechanism helps men achieve and maintain erections when sexually aroused.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Important note: <\/strong>Despite its long-lasting effects, Cialis does not cause erections without sexual stimulation.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">What Is Cialis Used For?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis\/tadalafil primarily treats erectile dysfunction (ED). The condition becomes more prevalent with age and may relate to various factors including health conditions, medications, <a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/therapy-for-men-with-ed\/\">mental health<\/a>, and lifestyle choices. Approximately <a href=\"https:\/\/www.niddk.nih.gov\/health-information\/urologic-diseases\/erectile-dysfunction\/definition-facts\">30 million American men<\/a> experience difficulty achieving or maintaining erections.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Beyond ED treatment, Cialis serves additional medical purposes:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Treatment of <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2868348\/\">pulmonary hypertension<\/a> (as Adcirca) since 2009<\/li>\n\n\n\n<li>Management of ED with benign prostatic hyperplasia (ED+BPH) since 2011<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Effectiveness of As-Needed vs. Once-Daily Cialis&nbsp;<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Clinical studies show Cialis and other <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4542406\/\">PDE5 inhibitors<\/a> effectively treat ED in 60-70% of men. While <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5411983\/\">both dosing options prove effective<\/a> for most men, <a href=\"https:\/\/investor.lilly.com\/news-releases\/news-release-details\/new-study-shows-men-taking-cialisr-tadalafil-tablets-once-daily\">research<\/a> indicates that some men who don&#8217;t respond to as-needed dosing may benefit from switching to daily low-dose treatment.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">How Does Cialis Work?<\/h4>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/penis-anatomy-flacid-and-erect.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"503\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/penis-anatomy-flacid-and-erect.jpg\" alt=\"penis anatomy flaccid and erect\" class=\"wp-image-39366\" style=\"width:780px\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/penis-anatomy-flacid-and-erect.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/penis-anatomy-flacid-and-erect-300x193.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/penis-anatomy-flacid-and-erect-768x495.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis works by inhibiting the PDE5 enzyme, which helps regulate blood pressure. This action improves blood flow to the penis, supporting the physical process of achieving an erection during sexual activity. However, Cialis doesn&#8217;t affect sexual desire or cause automatic erections.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">As-Needed Treatment\u00a0<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">For occasional ED treatment or planned sexual activity within 36 hours, as-needed Cialis offers flexibility. Most men take 10 or 20 milligrams of tadalafil to achieve desired results. This extended duration enables more spontaneous intimacy.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Daily Treatment\u00a0<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Lower doses of 2.5 or 5 milligrams allow for continuous treatment, maintaining steady medication levels for consistent results. This option particularly benefits men with ED+BPH and may reduce side effects compared to higher doses.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Benefits of Cialis and Daily Cialis<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/middle-aged-couple-higging-on-a-beach.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"520\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/middle-aged-couple-higging-on-a-beach.jpg\" alt=\"\" class=\"wp-image-39367\" style=\"width:780px\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/middle-aged-couple-higging-on-a-beach.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/middle-aged-couple-higging-on-a-beach-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/middle-aged-couple-higging-on-a-beach-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Both dosage options of Cialis help men achieve and maintain erections for more satisfying sexual experiences.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Benefits include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Enhanced sexual confidence<\/li>\n\n\n\n<li>Improved relationship satisfaction<\/li>\n\n\n\n<li>Better overall intimate experiences<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Does Cialis Improve Sexual Performance?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis and tadalafil work by improving blood flow\u2014they don\u2019t increase sexual desire or ability, and they don\u2019t directly cause an erection.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Instead, this treatment helps men achieve and maintain a firmer erection with sexual stimulation, which can lead to more satisfying sex.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis vs Natural Remedies<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">Natural Alternatives vs. Cialis<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">While some natural remedies claim to treat ED, including \u201c<a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/more-proof-that-herbal-viagra-just-doesnt-measure-up\/\">natural Viagra<\/a>\u201d and herbs like horny goat weed or foods like oysters, these alternatives have no supporting scientific evidence and may pose safety risks.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis, Cialis for daily use, and the generic tadalafil are FDA-approved treatments specifically designed to target ED. This prescription medication is a safer, more effective way to reliably manage ED under the supervision of a medical professional.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">How to Take As Needed and Daily Cialis<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"520\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/20mg-tadalafil-pills.jpg\" alt=\"20mg tadalafil pills\" class=\"wp-image-39368\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/20mg-tadalafil-pills.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/20mg-tadalafil-pills-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/20mg-tadalafil-pills-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis is available in tablet format, taken by mouth. Before you begin this or any ED medication, talk to your doctor (or one of ours) for a guide to Cialis. Make sure your healthcare provider knows about all of your chronic conditions and any other medications you take.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">As Needed Cialis Dosage Instructions<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The typical starting dose for as-needed Cialis is 10 milligrams, but this can be increased&nbsp; to 20 milligrams or reduced to 5 milligrams based on how well it works and any side effects.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Most men begin with 10 milligrams, but your doctor will determine the dose that\u2019s right for you. Never take more than one dose in a 24-hour period, regardless of the amount.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis for Daily Use Dosage Instructions<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Daily Cialis comes in lower doses, usually 2.5 or 5 milligrams, to provide consistent effects over time.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This lower dose is designed to be taken at the same time every day to maintain steady levels in your body. Always follow your doctor\u2019s instructions and don\u2019t exceed the prescribed dose.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">How to Take Cialis Pills<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Swallow Cialis tablets whole with water. Unlike Viagra, splitting Cialis tablets is not recommended because of its long-lasting formula. You can take Cialis with or without food, and it won\u2019t be affected by high-fat meals.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Best Time to Take Cialis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">For as-needed Cialis, take your dose about 30 minutes to an hour before you plan to have sex.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis for daily use should be taken at the same time every day, regardless of sexual activity.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">How Long Does As-Needed Cialis Last?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">As-needed Cialis can remain effective for up to 36 hours\u2014perfect for romantic weekend getaways.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">How Long Does Cialis for Daily Use Last?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Daily Cialis works continuously. As long as you take it every day, you can be ready for sexual activity at any time.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">What Happens if I Take Too Much Cialis?<\/h4>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"520\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/doctor-filling-a-chart-while-talking-to-a-male-patient.jpg\" alt=\"doctor filling out a chart while talking with a male patient\" class=\"wp-image-39369\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/doctor-filling-a-chart-while-talking-to-a-male-patient.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/doctor-filling-a-chart-while-talking-to-a-male-patient-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/doctor-filling-a-chart-while-talking-to-a-male-patient-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/cialis\/what-happens-if-you-take-too-much-cialis\/\">Taking too much Cialis<\/a> can lead to side effects like severe headaches, dizziness, low blood pressure, and other cardiovascular issues. Seek medical attention if you experience any severe side effects.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Because<a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/cialis\/how-long-does-cialis\/\"> Cialis lasts longer than other ED medications<\/a>, there\u2019s a higher risk that you could take too much. Always follow your doctor\u2019s dosing instructions. Make sure you understand the benefits and side effects of your medication.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Side Effects of Cialis<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Like all medications, Cialis can cause side effects. Tadalafil is not available over the counter because it could have dangerous interactions with certain medications or health conditions.&nbsp;&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Is Cialis Safe?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">For most men, Cialis is safe. In fact, some men switch from other ED medications because Cialis often has milder side effects. But because its active ingredient lasts longer in your bloodstream, certain side effects may also last longer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You should always talk to your doctor before taking this or any other medication. Men with certain health conditions, like serious heart or liver problems, or people taking <a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/list-of-nitrates\/\">nitrates<\/a> should not take Cialis.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis Side Effects<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Before taking an ED medication, take the time to understand<a href=\"https:\/\/www.fda.gov\/drugs\/postmarket-drug-safety-information-patients-and-providers\/questions-and-answers-cialis-tadalafil\"> the side effects of Cialis<\/a>. Because Cialis is a PDE5 inhibitor, most side effects are related to changes in blood flow.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Common side effects include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Headache. <\/strong>The most common side effect of Cialis is headaches, which accounts for around<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15036680\/\"> 15 percent of all reported side effects<\/a>.<\/li>\n\n\n\n<li><strong>Upset stomach.<\/strong> PDE5 inhibitors have an impact on the gastrointestinal tract, so some men experience heartburn, nausea, or belching.<\/li>\n\n\n\n<li><strong>Stuffy or runny nose.<\/strong> Because Cialis changes blood flow, taking this medication can impact the sensitive blood vessels in your sinuses.<\/li>\n\n\n\n<li><strong>Back pain. <\/strong>Increased circulation and muscle relaxation can lead to increased sensitivity to pain\u2014especially in the lower back.<\/li>\n\n\n\n<li><strong>Flushing.<\/strong><a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/viagra-facial-flushing\/\"> Facial flushing<\/a> is another common side effect of all PDE5 inhibitors. With increased blood flow throughout your body, you may experience red cheeks and a warm feeling.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Less-common side effects include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Dizziness.<\/strong> A temporary change in blood pressure can lead to dizziness or a sense of weakness.<\/li>\n\n\n\n<li><strong>Temporary vision changes. <\/strong>These are <a href=\"https:\/\/medical.lilly.com\/us\/products\/answers\/what-are-the-side-effects-of-cialis-tadalafil-on-vision-26435\">very rare with Cialis<\/a>, but some men experience blurry vision or changes in color vision. This side effect is more common (but still rare) with<a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra-and-vision-side-effects-why-switching-drugs-may-help\/\"> Viagra<\/a>.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis can also have serious side effects that require immediate medical attention. Rare but serious side effects can include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Priapism. <\/strong><a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/what-is-priapism\/\">Priapism<\/a>\u2014an erection lasting four or more hours\u2014might sound like a joke, but it\u2019s a serious condition that can cause <a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/erectile-tissue-damage\/\">damage to the penile tissue<\/a>. Thankfully, it\u2019s<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32622767\/\"> extraordinarily rare<\/a>.<\/li>\n\n\n\n<li><strong>Hypotension (low blood pressure).<\/strong> Cialis works by changing blood flow, and if you have existing heart conditions, this effect could lead to<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14609623\/\"> dangerously low blood pressure<\/a>.<\/li>\n\n\n\n<li><strong>Rash.<\/strong> Some people can experience mild itching or a rash. If you notice symptoms of an allergic reaction, call your doctor right away.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Cialis Risks and Contraindications<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/man-holding-a-bottle-of-pills-and-researching-on-his-phone-the-risks-and-side-effects.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"521\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/man-holding-a-bottle-of-pills-and-researching-on-his-phone-the-risks-and-side-effects.jpg\" alt=\"man holding a bottle of pills and researching on his phone the risks and side effects\" class=\"wp-image-39328\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/man-holding-a-bottle-of-pills-and-researching-on-his-phone-the-risks-and-side-effects.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/man-holding-a-bottle-of-pills-and-researching-on-his-phone-the-risks-and-side-effects-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/man-holding-a-bottle-of-pills-and-researching-on-his-phone-the-risks-and-side-effects-768x513.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Some people should not take Cialis or tadalafil. Others should use it with caution or under medical supervision.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Who Should Not Take Cialis?<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>People taking<a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/list-of-nitrates\/\"> nitrates<\/a><\/li>\n\n\n\n<li>People with serious cardiovascular conditions<\/li>\n\n\n\n<li>People with an allergy to tadalafil or other PDE5 inhibitors<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Who Should Take Cialis Only With Caution?<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>People with low blood pressure<\/li>\n\n\n\n<li>People taking alpha-blockers<\/li>\n\n\n\n<li>People with liver or kidney disease<\/li>\n\n\n\n<li>People with active stomach ulcers<\/li>\n\n\n\n<li>Individuals with a history of stroke or heart attack<\/li>\n\n\n\n<li>People with sickle cell anemia or leukemia because these can make priapism more likely<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Keep in mind that these lists are general guidelines. In special cases, doctors may feel the benefits of taking a particular medication outweigh the risks, so if you are in one of these groups, talk to your doctor about your personal situation.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cialis Drug Interactions<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Like most medications, Cialis can have drug interactions and side effects\u2014some of which can be serious. According to<a href=\"https:\/\/www.drugs.com\/drug-interactions\/tadalafil,cialis.html\"> Drugs.com<\/a>, a significant number of drugs and supplements can interact with this medication.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The most important potential interactions to be aware of include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Nitrates (nitroglycerin). <\/strong>These cardiovascular medications work in the same way as ED medications, by relaxing blood vessels and opening blood vessels. When combined with any PDE5 inhibitor, this can lead to a sudden, dangerous drop in blood pressure.<\/li>\n\n\n\n<li><strong>Alpha blockers and calcium channel blockers (doxazosin, tamsulosin, diltiazem). <\/strong>Taking alpha blockers and Cialis at the same time can lead to dangerously low blood pressure.<\/li>\n\n\n\n<li><strong>Antibiotics (clarithromycin, erythromycin) and antifungals (itraconazole, ketoconazole).<\/strong><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/021368s20s21lbl.pdf\"><strong> <\/strong>These drugs<\/a> may cause Cialis and other medications to build up in your bloodstream, worsening side effects.<\/li>\n\n\n\n<li><strong>Other erectile dysfunction medications (sildenafil, vardenafil, avanafil). <\/strong>Taking Cialis along with other ED medications can increase the risk of serious side effects like priapism and hypotension (low blood pressure).<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">You should not drink alcohol in excess with Cialis or tadalafil. Together, they can widen the blood vessels too much, leading to an unsafe drop in blood pressure in addition to worsened side effects like headache and dizziness.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For the complete known interactions list, visit the Drugs. <a href=\"https:\/\/www.drugs.com\/drug-interactions\/tadalafil,cialis-index.html\">Drug Interactions Checker<\/a>. However, no list of potential drug interactions is complete, so let your provider know if you experience any new or unusual symptoms after taking this medication.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">As-Needed Cialis and Cialis for Daily Use vs. Other ED Medications<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Second only to Viagra, Cialis is one of the best-known treatments for ED\u2014but you have<a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/which-ed-medication-is-right-for-me\/\"> even more choices<\/a>. Consider your needs and speak to your doctor before deciding on the treatment that\u2019s right for you.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis vs. Viagra<\/h4>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"520\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/10\/cialis-and-viagra-pill-boxes.jpg\" alt=\"cialis and viagra pill boxes\" class=\"wp-image-38777\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/10\/cialis-and-viagra-pill-boxes.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/10\/cialis-and-viagra-pill-boxes-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/10\/cialis-and-viagra-pill-boxes-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Viagra (sildenafil) was the first widely accepted ED treatment on the market. Cialis and Viagra are both PDE5 inhibitors, but there are major differences:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Duration and onset of action. <\/strong>Cialis kicks in after about 15 to 30 minutes, which is slightly faster than Viagra\u2019s 30- to 60-minute onset. Viagra lasts about four to six hours, but Cialis lasts up to 36 hours\u2014or indefinitely, when taken daily in the low-dose form.<\/li>\n\n\n\n<li><strong>Dosing options. <\/strong>Cialis has more options\u2014as-needed and low-dose for daily use. Viagra is only available as needed.<\/li>\n\n\n\n<li><strong>Side effects.<\/strong> Both drugs have similar side effects like headaches, flushing, and nasal congestion. However, some men find that Cialis is easier on their stomachs. Low-dose tadalafil has fewer reported side effects than higher doses.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis vs. Vardenafil<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.edrugstore.com\/vardenafil\/\">Vardenafil<\/a> (previously sold under the brand name Levitra) is another powerful PDE5 inhibitor to treat ED.&nbsp;&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Onset and duration. <\/strong>Vardenafil starts working after 30 to 60 minutes and continues working for up to six hours, which is considerably shorter than Cialis.<\/li>\n\n\n\n<li><strong>Strength. <\/strong>Vardenafil and tadalafil are both powerful, so you don\u2019t need to take a large dose to feel the effects. However, vardenafil shouldn\u2019t be taken daily.<\/li>\n\n\n\n<li><strong>Side effects. <\/strong>The<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=a01def95-c0ef-43b9-bd9e-5565b2385ad3\"> side effects for vardenafil<\/a> and Cialis are similar and generally milder than Viagra\u2019s. However, vardenafil has a shorter half-life, so side effects typically go away sooner than with long-acting Cialis.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis vs. Stendra<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.edrugstore.com\/stendra\/\">Stendra<\/a> (avanafil) is a newer generation PDE5 inhibitor with promising, rapid results for treating ED.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Onset and duration. <\/strong>Stendra can start working after just 15 minutes and can last up to six hours. That\u2019s about the same as Cialis, but again, Cialis has a much longer duration.<\/li>\n\n\n\n<li><strong>Generic options and cost. <\/strong>Cialis and Cialis for daily use are also available as the generic tadalafil, but currently, Stendra is only available by brand name and is more expensive.<\/li>\n\n\n\n<li><strong>Side effects.<\/strong> Stendra has a more selective action on the PDE5 enzyme, so it may have fewer side effects than Cialis and other ED treatments.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">What Is the Best ED Medication?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis, Viagra, vardenafil, and Stendra are all in the same drug class and work in approximately the same way. Your doctor will help you find the right treatment or the best Cialis alternative that has manageable side effects and relieves your ED.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cialis Pricing and Availability<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The cost and availability of Cialis varies depending on where you shop, whether you choose brand-name or generic, and whether your insurance will help cover the cost.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Cialis vs Tadalafil Cost<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">If price is your main concern, you\u2019ll probably prefer the generic form,<a href=\"https:\/\/www.edrugstore.com\/tadalafil\/\"> tadalafil<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Across all pharmacies, brand-name as-needed Cialis currently costs around $60 per tablet for 20 milligrams. Cialis for daily use costs a little more than $13 per tablet for 5 milligrams. Tadalafil costs an average of $6.78 for 20 milligrams and $2.10 for 5 milligrams.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Is Cialis Covered by Insurance?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">When used to treat erectile dysfunction with no other medical need, Cialis is probably not covered by your insurance. If you need tadalafil for benign prostate hyperplasia or pulmonary hypertension, however, your insurance probably will cover your prescriptions.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Always check with your insurance provider for coverage details.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Where Can I Find Cialis Discounts?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">eDrugstore offers great deals for 50 or even 75 percent off on select products each month. Shop in bulk for extra savings and discounts\u2014and always free delivery.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Is It Safe to Buy Cialis Online?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Yes! Always choose a reputable online source, like eDrugstore, to buy ED meds online. Remember, Cialis is by prescription only, so only shop with licensed pharmacies that require a valid prescription.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Watch out for other<a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/buying-viagra-online\/\"> common mistakes<\/a> so you can shop safely and make sure you\u2019re always getting FDA-approved, genuine medications.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The Advantages of Buying Cialis and Cialis for Daily Use Online from eDrugstore<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/erectile-dysfunction-on-a-medical-form.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"520\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/erectile-dysfunction-on-a-medical-form.jpg\" alt=\"erectile dysfunction on a medical form\" class=\"wp-image-39370\" style=\"width:780px\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/erectile-dysfunction-on-a-medical-form.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/erectile-dysfunction-on-a-medical-form-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/12\/erectile-dysfunction-on-a-medical-form-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">With eDrugstore, delivery of Cialis or Cialis for daily use is just a few clicks away. It\u2019s an easy, discreet, and safe way to manage your ED without the hassle of a doctor\u2019s visit.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Easy and convenient.<\/strong> You don\u2019t need an appointment to get your medication from eDrugstore. Our U.S. licensed pharmacists will check your health and help you find the right medication for you.<\/li>\n\n\n\n<li><strong>Guaranteed quality.<\/strong> You\u2019ll only find FDA-approved, genuine medications at eDrugstore.<\/li>\n\n\n\n<li><strong>Cost savings.<\/strong> Get a free medical consultation, free shipping, and special discounts up to 75 percent off with eDrugstore. Be sure to check for bulk buying options to save on Cialis for daily use.<\/li>\n\n\n\n<li><strong>Complete privacy.<\/strong> Your order ships in fast, discreet packaging to keep your order private, and we\u2019ll never share or sell your personal information.<\/li>\n\n\n\n<li><strong>24\/7 support.<\/strong> Have questions? eDrugstore\u2019s licensed pharmacists are always available to assist you.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Be Ready for Anything with Cialis<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Cialis is the longest-lasting <a href=\"https:\/\/www.edrugstore.com\/erectile-dysfunction\/?__mscta=2392_102878_15220\">erectile dysfunction<\/a> drug on the market, and it\u2019s the only one that\u2019s available in a low daily dose. If you&#8217;re wondering whether it\u2019s right for you, eDrugstore offers a free medical consultation with a licensed U.S. physician to help you decide.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You can order with confidence from eDrugstore, where it\u2019s always safe to<a href=\"https:\/\/www.edrugstore.com\/cialis\/\"> buy Cialis, Cialis for daily use, or tadalafil online<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Disclaimer: This article provides general information about health and related topics but is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Find out how Cialis helps with ED. Our ultimate guide to Cialis and its generic, tadalafil, has everything you need to know, from safety to effectiveness.<\/p>\n","protected":false},"author":12,"featured_media":36373,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[47,20,17],"tags":[186,22,408,23,400,194,184],"class_list":["post-39364","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cialis","category-erectile-dysfunction","category-viagra","tag-cialis","tag-ed","tag-ed-treatment","tag-erectile-dysfunction-2","tag-erectile-dysfunction-drugs","tag-male-impotence","tag-viagra"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Highlights: Cialis (tadalafil) treats erectile dysfunction (ED), helping men achieve and maintain firmer erections. 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