{"id":37033,"date":"2024-04-17T13:20:35","date_gmt":"2024-04-17T06:20:35","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=37033"},"modified":"2024-04-18T03:14:49","modified_gmt":"2024-04-17T20:14:49","slug":"flonase-vs-astelin","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/allergy-relief\/flonase-vs-astelin\/","title":{"rendered":"Flonase vs Astelin for Seasonal Allergies: Which Is Better?"},"content":{"rendered":"<p><strong>Highlights\u00a0<\/strong><\/p>\n<ul>\n<li aria-level=\"1\"><strong>Over 81 million people suffer from seasonal allergies in the U.S.<\/strong><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><strong>Drugs like Flonase and Astelin can improve sufferers\u2019 quality of life significantly.<\/strong><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><strong>Flonase vs. Astelin: Which is more effective with fewer side effects?<\/strong><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><strong>eDrugstore offers you low prices on these drugs and a complimentary consultation with a U.S.-licensed doctor.<\/strong><\/li>\n<\/ul>\n<hr \/>\n\n<blockquote>\n<blockquote class=\"blockquote\"><p>\u201cNature is a wonderful thing. Nature does not love me, though.\u201d \u2013 Jennie Koeper<\/p><\/blockquote>\n<\/blockquote>\n<p>In 2021, <a href=\"https:\/\/stacks.cdc.gov\/view\/cdc\/122809\">81 million<\/a> people struggled with seasonal allergic rhinitis in the U.S. That means 26 percent of adults and 19 percent of children suffer from stuffy noses and other allergic symptoms. Seasonal allergies are severe quality-of-life destroyers for many.<\/p>\n<p>But solutions exist, including accessible, <a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-nasal-antihistamine-nonprescription-use\">over-the-counter<\/a> medications like Flonase and Astelin. Flonase is a corticosteroid while Astelin is an antihistamine. Which one is better? Let\u2019s settle the Flonase vs. Astelin debate for good!<\/p>\n<h3>Flonase vs. Astelin: The Basics<\/h3>\n<p>Over-the-counter or prescription allergy sprays like Astelin and Flonase are your most straightforward options for <a href=\"https:\/\/www.edrugstore.com\/blog\/allergy-relief\/combating-allergy-season\/\">seasonal allergy treatment<\/a>. How do they work, and how effective are they for seasonal allergies?<\/p>\n<h4>Flonase<\/h4>\n<p><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2019\/020121s045lbl.pdf\">Flonase<\/a> is an over-the-counter nasal spray for the treatment of seasonal allergy symptoms. The active substance in Flonase is a corticosteroid called fluticasone propionate, better known to most as simply fluticasone. Flonase is recommended for adult patients and children over four.<\/p>\n<p>Fluticasone modulates the constriction and widening of blood vessels and reduces inflammation. It blocks cells that create inflammation in the nose, like eosinophils, monocytes, and macrophages, and boosts the action of anti-inflammatory substances. The drug can reduce stuffiness by constricting blood vessels in the lining of the nose.<\/p>\n<h4>Astelin<\/h4>\n<p>Astelin is a nasal spray that uses azelastine hydrochloride as its active substance. It works by blocking histamine receptors in the lining of the nasal passage. Histamine <a href=\"https:\/\/journals.physiology.org\/doi\/full\/10.1152\/japplphysiol.00689.2019\">widens blood vessels<\/a>, leading to nasal congestion. It also causes inflammation. Antihistamines cause the smooth muscles to constrict blood vessels, and inflammation fizzles out.<\/p>\n<p>Here\u2019s a quick head-to-head comparison of the basics.<\/p>\n\n<table id=\"tablepress-120\" class=\"tablepress tablepress-id-120\">\n<thead>\n<tr class=\"row-1\">\n\t<td class=\"column-1\"><\/td><th class=\"column-2\">Flonase<\/th><th class=\"column-3\">Astelin<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">Active Ingredient<\/td><td class=\"column-2\">Fluticasone propionate (steroid)<\/td><td class=\"column-3\">Azelastine hydrochloride (antihistamine)<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">How it Works<\/td><td class=\"column-2\">Reduces inflammation in the nasal passages and constricts blood vessels.<\/td><td class=\"column-3\">Blocks histamine receptors, reducing allergy symptoms.<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">Overview<\/td><td class=\"column-2\">Prescription or over-the-counter steroid nasal spray for allergic rhinitis and non-allergic rhinitis. May take a few days to show full effect.<\/td><td class=\"column-3\">Prescription or OTC nasal spray for allergic rhinitis. Works quickly, within minutes, to relieve symptoms.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-120 from cache -->\n<h3>Effectiveness for Seasonal Allergies<\/h3>\n<p>The most relevant part of the Astelin vs. Flonase battle is the efficacy-wise comparison of the two drugs.<\/p>\n<p>Their effectiveness for seasonal allergy symptoms is <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9702036\/\">comparable<\/a>, but some differences may tip the scale one way or the other, depending on the unique needs of patients.<\/p>\n<p>Researchers agree that the two solutions work equally well, but azelastine works faster than fluticasone.<\/p>\n<p>A <a href=\"https:\/\/www.ingentaconnect.com\/content\/ocean\/aap\/2012\/00000033\/00000006\/art00002\">2012 study<\/a> found that around 50 percent of fluticasone and azelastine test subjects achieved a 50 percent reduction in their allergic rhinitis nasal symptoms. After 14 days of treatment, however, 53 percent of azelastine patients had experienced 50 percent reductions in their symptoms, compared to just 39 percent of fluticasone patients over the same period.<\/p>\n<p>Azelastine \u201ckicks in\u201d within <a href=\"https:\/\/journals.sagepub.com\/doi\/abs\/10.2500\/ajr.2007.21.3058\">15 minutes<\/a> of administration. Fluticasone\u2019s first therapeutic effects appear in <a href=\"https:\/\/www.annallergy.org\/article\/S1081-1206(10)63300-5\/abstract\">two to four hours<\/a>, but it can take up to 12 hours to act.<\/p>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/young-woman-experiencing-seasonal-allergies.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-37037 size-full aligncenter\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/young-woman-experiencing-seasonal-allergies.jpg\" alt=\"young woman experiencing seasonal allergies\" width=\"780\" height=\"520\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/young-woman-experiencing-seasonal-allergies.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/young-woman-experiencing-seasonal-allergies-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/young-woman-experiencing-seasonal-allergies-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/a><\/p>\n<h4>Conclusions:<\/h4>\n<ul>\n<li aria-level=\"1\">Astelin and Flonase work equally well for allergic rhinitis.<\/li>\n<li aria-level=\"1\">Astelin works faster.<\/li>\n<li aria-level=\"1\">Astelin has a better safety profile.<\/li>\n<li aria-level=\"1\">Doctors can prescribe or recommend Astelin to more patients than Flonase.<\/li>\n<li aria-level=\"1\">Astelin may be a safer solution for children and patients suffering from glaucoma and cataracts.<\/li>\n<\/ul>\n<p>Some patients may not have to choose between Astelin and Flonase for allergies. The best nasal spray for allergies may be a combination of the two. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2621402\/\">A combination<\/a> of azelastine and fluticasone can be a more effective allergy treatment than either agent used alone.<\/p>\n<h3><span style=\"font-weight: 400;\">Flonase vs. Astelin Side Effects Comparison<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">We can\u2019t assess the effectiveness of a medication without considering its side effects. A drug\u2019s unwanted and undesirable effects can negate its benefits, rendering patients unable to take it. Both Flonase and Astelin produce side effects, ranging from mildly unpleasant to disruptive. Side effects differ from one patient to another.<\/span><\/p>\n<h3>Flonase vs. Astelin Side Effects Comparison<\/h3>\n<p>We can\u2019t assess the effectiveness of a medication without considering its side effects. A drug\u2019s unwanted and undesirable effects can negate its benefits, rendering patients unable to take it. Both Flonase and Astelin produce side effects, ranging from mildly unpleasant to disruptive. Side effects differ from one patient to another.<\/p>\n\n<table id=\"tablepress-121\" class=\"tablepress tablepress-id-121\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\">Side Effect<\/th><th class=\"column-2\">Flonase (Fluticasone)<\/th><th class=\"column-3\">Astelin (Azelastine)<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">Common<\/td><td class=\"column-2\">Headache, nasal burning\/irritation, sneezing, dry mouth, throat irritation, unpleasant taste<\/td><td class=\"column-3\">Bitter taste in mouth, drowsiness, tiredness, nasal burning\/irritation, sneezing, runny\/stuffy nose, headache, red eyes<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">Rare<\/td><td class=\"column-2\">Nosebleeds, burning\/crusting in the nose, slowed wound healing, vision problems, increased risk of infection with long-term use<\/td><td class=\"column-3\">Nosebleeds, severe fatigue, allergic reaction (hives, swelling, wheezing)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-121 from cache -->\n<p>Astelin\u2019s bitter taste may be a dosage-related problem. If it results from an incorrect dosage, it\u2019s easy to minimize.<\/p>\n<p>Using the two medications together may increase the frequency and intensity of side effects.<\/p>\n<h3>Flonase vs. Astelin Drug Interactions<\/h3>\n<p>Both medications can interact with foods, beverages, vitamins, supplements, and other drugs. Talk to your doctor about your medications, supplements, and vitamins before using Flonase or Astelin for seasonal allergies.<\/p>\n<p>The two drugs can produce potentially dangerous interactions with:<\/p>\n<ul>\n<li aria-level=\"1\">Alcohol (increases drowsiness)<\/li>\n<li aria-level=\"1\">Other medications that cause sleepiness<\/li>\n<li aria-level=\"1\">Central nervous system depressants, like opioids<\/li>\n<li aria-level=\"1\">Anxiety medications<\/li>\n<li aria-level=\"1\">Seizure drugs<\/li>\n<li aria-level=\"1\">Muscle relaxants<\/li>\n<li aria-level=\"1\">Sleeping pills<\/li>\n<li aria-level=\"1\">Antifungal medications<\/li>\n<li aria-level=\"1\">HIV protease inhibitors<\/li>\n<\/ul>\n<p>If you take both Flonase and Astelin, you increase the spectrum of potential drug interactions.<\/p>\n<p>This list of drug interactions is not complete. Both drugs may interact with many other medications. Visit the <a href=\"https:\/\/www.drugs.com\/drug_interactions.html\">Drugs.com Interaction Checker<\/a> for potential interactions with other medications you may be taking.<\/p>\n<p><span style=\"font-size: calc(1.3rem + 0.6vw); background-color: var(--bs-body-bg); color: var(--bs-body-color); font-family: var(--bs-body-font-family); text-align: var(--bs-body-text-align);\">Cost and Availability<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your doctor may prescribe Flonase or Astelin for seasonal allergies, but both drugs and their generic equivalents are available over the counter.<\/span><\/p>\n<p>Prescription Flonase is <a href=\"https:\/\/www.drugs.com\/flonase.html\">the same<\/a> as OTC Flonase.<\/p>\n<p>The FDA approved azelastine hydrochloride for OTC use in 2021.<\/p>\n<p>According to <a href=\"https:\/\/www.drugs.com\/price-guide\/flonase\">Drugs.com<\/a>:<\/p>\n<ul>\n<li aria-level=\"1\">A 16 gram Flonase spray costs from $91.62 to $107. You can buy generic fluticasone nasal sprays from $11.97 for 9.9 milliliters.<\/li>\n<li aria-level=\"1\">A 30 milliliter Astelin nasal spray costs $70.38. Generic azelastine sprays are available from $36.96 per 30 milliliters.<\/li>\n<\/ul>\n<p>Prices can vary depending on your insurance, patient assistance programs, coupons, and rebates you may get.<\/p>\n<p><span style=\"font-size: calc(1.3rem + 0.6vw); background-color: var(--bs-body-bg); color: var(--bs-body-color); font-family: var(--bs-body-font-family); text-align: var(--bs-body-text-align);\">User Experiences and Preferences<\/span><\/p>\n<h4>Flonase\/fluticasone<\/h4>\n<p><span style=\"font-weight: 400;\">Flonase users left 68 reviews at <\/span><a href=\"https:\/\/www.drugs.com\/comments\/fluticasone-nasal\/flonase.html\"><span style=\"font-weight: 400;\">Drugs.com<\/span><\/a><span style=\"font-weight: 400;\">. Thirty-eight percent of users report positive experiences with the drug, while 51 percent share negative experiences.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Those with positive experiences point to fewer allergy-related headaches, less nasal congestion, and clearer sinuses.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Complaints include back pain, panic attacks, out-of-control anxiety, headaches, and disrupted sleep.<\/span><\/p>\n<h4>Astelin\/azelastine<\/h4>\n<p><span style=\"font-weight: 400;\">Astelin users left <\/span><a href=\"https:\/\/www.drugs.com\/comments\/azelastine-nasal\/astelin-for-allergic-rhinitis.html\"><span style=\"font-weight: 400;\">19 reviews<\/span><\/a><span style=\"font-weight: 400;\">, of which 84 percent are positive and 5 percent are negative.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some users hail Astelin as a \u201cmiracle cure.\u201d Others say they only see mild or no side effects from the drug.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">On the downside, one person complained of a burned nose and throat, while another found the bitter aftertaste of the drug unbearable.<\/span><\/p>\n<h4>Many Users Prefer Astelin<\/h4>\n<p><span style=\"font-weight: 400;\">The available user reviews on Flonase and Astelin favor the latter. Astelin has less feedback, however, as it is a drug that only became available for OTC use recently.<\/span><\/p>\n<h3>Flonase vs. Astelin: Which is Right for You?<\/h3>\n<p><span style=\"font-weight: 400;\">Flonase and Astelin appear to be equally effective at relieving allergy symptoms. However, the efficacy of the medications may differ from person to person.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Flonase casts a wider net in its fight against allergic rhinitis symptoms, blocking more potential symptom-causing factors.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Astelin is gentler, with a more attractive safety profile. Research shows it may be safer for children and people suffering from glaucoma and cataracts. Astelin may also provide quicker relief than Flonase.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The side effect profiles of the two medications are slightly different, but remember that not all individuals will experience the same side effects. If you find the side effects of one medication overwhelming, try the other.<\/span><\/p>\n<h3>Final Thoughts<\/h3>\n<p><span style=\"font-weight: 400;\">When choosing between Flonase and Astelin, consider the following factors:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Efficacy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Safety profile<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Side effect frequency and intensity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Onset speed<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">User preferences and feedback<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs you use and any underlying health conditions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Always consult with a qualified healthcare provider for a personalized treatment plan.<\/span><\/p>\n<h3>eDrugstore Can Help<\/h3>\n<p><span style=\"font-weight: 400;\">We carry both fluticasone (Flonase) and azelastine (Astelin) at better prices than those mentioned above.<\/span><\/p>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/buying-allegy-medicine-at-a-drugstore.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-37040 aligncenter\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/buying-allegy-medicine-at-a-drugstore.jpg\" alt=\"buying allegy medicine at a drugstore\" width=\"780\" height=\"520\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/buying-allegy-medicine-at-a-drugstore.jpg 780w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/buying-allegy-medicine-at-a-drugstore-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/04\/buying-allegy-medicine-at-a-drugstore-768x512.jpg 768w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/a><\/p>\n<p>When you become an eDrugstore client, you can take advantage of a complimentary consultation with a U.S.-licensed physician. Our doctors can help you choose the right medication for you and write your prescription for the <a href=\"https:\/\/www.edrugstore.com\/allergy-relief\/\">allergy relief<\/a> medication of your choice.<\/p>\n<p>Create an account and place your order now. When you shop with eDrugstore, shipping is always free.<\/p>\n<p><em>Disclaimer: This article provides general information about health and related topics but is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Flonase vs. Astelin is a question you must settle to find the optimal treatment for your seasonal allergies. Learn which of these drugs suits your needs better. <\/p>\n","protected":false},"author":22,"featured_media":37034,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[12],"tags":[],"class_list":["post-37033","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allergy-relief"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Flonase vs. Astelin is a question you must settle to find the optimal treatment for your seasonal allergies. 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