{"id":34273,"date":"2023-02-22T14:56:13","date_gmt":"2023-02-22T07:56:13","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=34273"},"modified":"2025-02-13T10:51:19","modified_gmt":"2025-02-13T03:51:19","slug":"what-to-do-when-cialis-stops-working","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/what-to-do-when-cialis-stops-working\/","title":{"rendered":"What To Do When Cialis Stops Working"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Cialis is an ED drug that may stop working due to incorrect use, health changes, or underlying physical problems.<\/strong><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>It\u2019s important to assess whether any lifestyle changes, new medications, or exacerbations of chronic disease are to blame.<\/strong><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Making adjustments to your lifestyle, asking your doctor to adjust your Cialis dose, or trying a new erectile dysfunction drug may help.<\/strong><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"font-weight: 400;\"><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cialis is a PDE5 inhibitor that makes it easier to achieve and sustain an erection. When it stops working after a period of successful use, it\u2019s natural to feel frustrated.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When Cialis stops working, improving your overall health or taking a higher dose may help. Understanding more about the potential causes can make it easier for you to get your ED treatment back on track.<\/span><\/p>\n<p><a href=\"https:\/\/www.edrugstore.com\/bg-ed\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-40406 size-full\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/01\/27122024-Generic-Viagra.png\" alt=\"Generic Viagra for erectile dysfunction\" width=\"745\" height=\"300\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/01\/27122024-Generic-Viagra.png 745w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2024\/01\/27122024-Generic-Viagra-300x121.png 300w\" sizes=\"auto, (max-width: 745px) 100vw, 745px\" \/><\/a><\/p>\n<h3>How Does Cialis Work?<\/h3>\n<p><span style=\"font-weight: 400;\">To achieve and maintain an erection, there must be more blood flow entering the arteries of your penis than exiting it. Increased blood flow occurs when neurotransmitters send signals to the arteries in your penis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cialis makes achieving an erection easier by increasing the number of neurotransmitters that encourage increased blood flow in penile arteries. ED medications work by blocking PDE5, which allows the blood vessels to relax and accommodate more blood. Cialis\u2019 effects last between 24 and 36 hours.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In order for cialis to become or remain effective, it needs to operate in the right environment. Multiple factors, including arousal and exacerbations of chronic disease, may work against it.<\/span><\/p>\n<h3>Why Does Cialis Stop Working?<\/h3>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/2.jpeg-64_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34278\" title=\"Man stressing out\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/2.jpeg-64_11zon.jpg\" alt=\"Man stressing out\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/2.jpeg-64_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/2.jpeg-64_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Cialis can stop working for multiple reasons. Some of them may be within your control. Here are some things to try so you can continue seeing the benefits of the drug.<\/span><\/p>\n<h4>Not Using Cialis Correctly<\/h4>\n<p><span style=\"font-weight: 400;\">Not using cialis correctly can stop it from working. Examples of incorrect use include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Dose. <\/b><span style=\"font-weight: 400;\">If you have certain chronic diseases, such as diabetes, you may need a higher dose.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Time of use.<\/b><span style=\"font-weight: 400;\"> Cialis may not work the first time you use it. It\u2019s important to try the medication several times before assuming it won\u2019t work.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Poor timing.<\/b><span style=\"font-weight: 400;\"> Make sure you use Cialis around one to two hours before intercourse.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Other medications<\/b><span style=\"font-weight: 400;\">. If you\u2019ve recently started taking another medication, speak to your doctor to learn if it might interact with Cialis.\u00a0<\/span><\/li>\n<\/ul>\n<h4>Physical Factors That May Stop Cialis from Working<br \/>\n<b><\/b><\/h4>\n<p><span style=\"font-weight: 400;\">A number of chronic health conditions can prevent Cialis from working, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Diabetes.<\/b><span style=\"font-weight: 400;\"> Evidence shows that suffering from <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7870518\/\"><span style=\"font-weight: 400;\">peripheral neuropathy<\/span><\/a><span style=\"font-weight: 400;\"> can make erectile dysfunction more likely. When the nervous centers that control blood flow to the penis are affected, Cialis may become less effective.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Hypertension.<\/b><span style=\"font-weight: 400;\"> Some of the drugs prescribed for high blood pressure can worsen ED. Diuretics such as hydrochlorothiazide and beta blockers like atenolol may make it difficult to achieve an erection, even with the help of an ED medication.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Vascular disease.<\/b> <a href=\"https:\/\/www.edrugstore.com\/medical-experts\/steven-a-schlosser-md\/venous-leak-vascular-disease-and-erectile-dysfunction\/\"><span style=\"font-weight: 400;\">Worsening vascular disease<\/span><\/a><span style=\"font-weight: 400;\"> can also affect blood flow to the penis.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Obesity. <\/b><span style=\"font-weight: 400;\">Obesity can affect how effective one part of the brain is in <\/span><a href=\"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/168\/3\/445.xml\"><span style=\"font-weight: 400;\">encouraging the release of testosterone<\/span><\/a><span style=\"font-weight: 400;\">. As testosterone is important for coordinating erections with sexual desire, not having enough of it can reduce Cialis\u2019 efficacy. Also, fat cells make estrogen in both men and women, which opposes testosterone in the body.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Renal insufficiency.<\/b><span style=\"font-weight: 400;\"> Suffering from renal insufficiency or chronic kidney disease (CKS) can cause blood vessels throughout the body to narrow, including the penis. Suffering from kidney disease may also lower testosterone. A <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5815543\/\"><span style=\"font-weight: 400;\">decrease in the glomerular filtration rate<\/span><\/a><span style=\"font-weight: 400;\"> can make ED more likely.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>High prolactin levels.<\/b><span style=\"font-weight: 400;\"> High prolactin levels can occur with some pituitary gland tumors or when taking certain antipsychotics. <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022395621005215?via%3Dihub\"><span style=\"font-weight: 400;\">High prolactin<\/span><\/a><span style=\"font-weight: 400;\"> may cause erectile dysfunction because it is the hormone responsible for the refractory period between orgasms.<\/span><\/li>\n<\/ul>\n<h3>What Can You Do When Cialis Doesn&#8217;t Work?<\/h3>\n<p><span style=\"font-weight: 400;\">If you\u2019re new to taking Cialis and it isn\u2019t working, it\u2019s important to assess whether you\u2019re taking it properly. Try the following to increase your chances of success:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take Cialis at least one hour before intercourse.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If you need to take Cialis every day, take it at the same time each day.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid taking Cialis with high fat foods, as they may slow down its release and reduce its efficacy.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ask your doctor for a medication review, as some medications containing nitrates can affect how Cialis works.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid using alcohol when taking Cialis.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid drinking grapefruit juice, as it may affect <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7003282\/\"><span style=\"font-weight: 400;\">how your body metabolizes Cialis<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<\/ul>\n<h3>What Can You Do If Cialis Stops Working After Successful Use?<\/h3>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/4.jpeg-29_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34277\" title=\"Older man working out\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/4.jpeg-29_11zon.jpg\" alt=\"Older man working out\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/4.jpeg-29_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/02\/4.jpeg-29_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Finding that Cialis stops working after a period of it being effective is especially frustrating. However, personal, mental, and physical changes can all make Cialis less effective.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If Cialis is less effective than usual, try the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Assess your chronic diseases. <\/b><span style=\"font-weight: 400;\">If you suffer from a chronic disease such as diabetes or hypertension, assess whether you\u2019re managing it as well as you can. Worsening chronic disease can also mean that you need a higher dose of Cialis than normal, so discuss changes with your doctor.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Change medications.<\/b><span style=\"font-weight: 400;\"> Starting a new medication may reduce Cialis\u2019 efficacy. Your doctor may be able to prescribe an alternative drug.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Review your lifestyle.<\/b><span style=\"font-weight: 400;\"> Perform an honest assessment of your lifestyle and make changes if necessary. Exercising, eating a balanced diet, and drinking alcohol in moderation make it easier for Cialis to work.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Reduce stress.<\/b><span style=\"font-weight: 400;\"> If you\u2019re going through a period of stress, it\u2019s difficult to become aroused. As you need arousal for Cialis to work, <\/span><a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/life-stress-and-erectile-dysfunction-how-to-take-control\/\"><span style=\"font-weight: 400;\">stress management<\/span><\/a><span style=\"font-weight: 400;\"> is crucial.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Try therapy.<\/b><span style=\"font-weight: 400;\"> Experiencing difficulties within your relationship can also affect your ability to become aroused. Relationship challenges can become particularly problematic when they relate to sex. Try speaking to a therapist as a couple to overcome relationship difficulties.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Schedule a checkup.<\/b><span style=\"font-weight: 400;\"> Sometimes an underlying condition that\u2019s showing no symptoms can stop Cialis from working. A checkup with your doctor will allow you to identify hidden problems.<\/span><\/li>\n<\/ul>\n<h3>If Cialis Stops Working, Should You Try Another ED Drug?<\/h3>\n<p><span style=\"font-weight: 400;\">When Cialis stops working, you may want to explore whether another ED drug could help. ED drugs such as <\/span><a href=\"https:\/\/www.edrugstore.com\/erectile-dysfunction\/sildenafil-citrate-ajanta\/\"><span style=\"font-weight: 400;\">sildenafil<\/span><\/a><span style=\"font-weight: 400;\"> (Viagra) and <\/span><a href=\"https:\/\/www.edrugstore.com\/erectile-dysfunction\/vardenafil\/\"><span style=\"font-weight: 400;\">vardenafil<\/span><\/a><span style=\"font-weight: 400;\"> (Levitra) also act as PDE5 inhibitors, but their active ingredients are different.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Trying another ED drug may be especially appropriate if you\u2019re taking a new medication. Cialis takes up to 36 hours to leave your system. In contrast, sildenafil and vardenafil last up to six hours, which may give you more room to take other medications and still experience their benefits.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Always consult with a medical professional before switching to a different medication.<\/span><\/p>\n<h3>Find the Best Prices for Cialis and Other ED Drugs with eDrugstore<\/h3>\n<p><span style=\"font-weight: 400;\">Discovering that your Cialis has stopped working doesn\u2019t need to be the end of the line for your ED treatment. At eDrugstore, we offer consultations with licensed medical professionals who can help you find the right treatment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">At eDrugstore, we can help you find the best fit and process your order quickly and discreetly. Find the right <\/span><a href=\"https:\/\/www.edrugstore.com\/\"><span style=\"font-weight: 400;\">erectile dysfunction drug<\/span><\/a><span style=\"font-weight: 400;\"> for you and place your order with confidence.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Do you know what to do when Cialis stops working? At eDrugstore, we can help explore alternative options when your ED drugs aren&#8217;t effective.<\/p>\n","protected":false},"author":1,"featured_media":36411,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[47,20],"tags":[],"class_list":["post-34273","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cialis","category-erectile-dysfunction"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Do you know what to do when Cialis stops working? 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