{"id":34065,"date":"2023-01-11T14:33:09","date_gmt":"2023-01-11T07:33:09","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=34065"},"modified":"2023-01-12T14:38:21","modified_gmt":"2023-01-12T07:38:21","slug":"essm-fertility-option-for-transgender-women","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/current-health-news\/essm-fertility-option-for-transgender-women\/","title":{"rendered":"ESSM: A New Fertility Option for Transgender Women?"},"content":{"rendered":"<p><b>Highlights\u00a0<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><b>Transgender women often struggle with fertility issues as a result of long-term hormonal therapies.<\/b><\/li>\n<li aria-level=\"1\"><b>Fertility options for transgender women include \u201cnatural\u201d conception, sperm cryopreservation, and microsurgical testicular sperm extraction (microTESE).<\/b><\/li>\n<li aria-level=\"1\"><b>The extended sperm search and microfreeze (ESSM) procedure allows providers to find and preserve sperm in people with low sperm counts who were unsuccessful with other retrieval methods.\u00a0<\/b><\/li>\n<li aria-level=\"1\"><b>The ESSM procedure is efficient and less invasive than microTESE.<\/b><\/li>\n<\/ul>\n<hr \/>\n<p><span style=\"font-weight: 400;\">Transgender women may have a better chance at having children, thanks to a procedure recently developed for men with low sperm counts. The extended sperm search and microfreeze (ESSM) technique is advanced, efficient, and less invasive than traditional sperm collection and preservation methods.<\/span><\/p>\n<h3>Overview<\/h3>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6626312\/\"><span style=\"font-weight: 400;\">Transgender people<\/span><\/a><span style=\"font-weight: 400;\"> who undergo gender-affirming care often face infertility. The extended sperm search &amp; microfreeze (ESSM) is a novel technique that helps providers find and freeze sperm in people with low sperm counts. ESSM has emerged as a potential option for transgender women hoping to have children.\u00a0<\/span><\/p>\n<h4>Fertility Challenges for Transgender Women<\/h4>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/current-health-news\/transgender-vs-transsexual\/\"><span style=\"font-weight: 400;\">Transgender<\/span> <\/a><span style=\"font-weight: 400;\">women receiving gender-affirming medical or surgical therapies are at risk for infertility. This is disheartening, as some <\/span><a href=\"https:\/\/www.familyequality.org\/wp-content\/uploads\/2019\/02\/LGBTQ-Family-Building-Study_Jan2019-1.pdf#page=4\"><span style=\"font-weight: 400;\">research<\/span><\/a><span style=\"font-weight: 400;\"> shows that transgender women report wanting to become parents at the same rate as other LGBTQIA+ people.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Long-term <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6626312\/\"><span style=\"font-weight: 400;\">hormonal therapy<\/span><\/a><span style=\"font-weight: 400;\"> makes it challenging to retrieve viable sperm from transgender women. Medication that suppresses testosterone and increases estrogen can decrease or even cease sperm production. Some transgender women have their testicles removed, which makes sperm retrieval impossible.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/publications.aap.org\/pediatrics\/article\/144\/3\/e20183943\/38417\/Fertility-Preservation-Outcomes-in-Adolescent-and?autologincheck=redirected\"><span style=\"font-weight: 400;\">Research<\/span><\/a><span style=\"font-weight: 400;\"> suggests that some transgender women may be able to regain sperm production after pausing hormonal therapy, but this is not guaranteed. What\u2019s more, pausing gender-affirming care can have a devastating impact on someone\u2019s mental and emotional well-being.\u00a0<\/span><\/p>\n<h4>Fertility Options for Transgender Women<\/h4>\n<p><a href=\"https:\/\/www.endocrine.org\/news-and-advocacy\/news-room\/2017\/many-transgender-individuals-consider-their-fertility-important-survey-shows\"><span style=\"font-weight: 400;\">Surveys<\/span><\/a><span style=\"font-weight: 400;\"> confirm that the vast majority of transgender people believe fertility counseling should be provided prior to beginning gender-affirming care. Those who have undergone long-term hormone therapy or who have their testicles removed have limited options for having children. Accessing fertility options early on provides transgender people with more options for having children in the future.<\/span><\/p>\n<p><a href=\"https:\/\/www.familyequality.org\/2019\/10\/02\/trans-women-and-fertility-what-we-know-what-dont-know-and-what-you-can-do\/\"><span style=\"font-weight: 400;\">Fertility options<\/span><\/a><span style=\"font-weight: 400;\"> for transgender women currently include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u201cNatural\u201d conception.<\/b><span style=\"font-weight: 400;\"> If a transgender woman still produces sperm and has a partner with a uterus, they may be able to conceive through sex. However, this depends on a number of factors, including sperm count and motility. Natural conception typically requires pausing all hormonal therapies.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Sperm cryopreservation.<\/b><span style=\"font-weight: 400;\"> Transgender women can freeze and store their sperm using sperm cryopreservation so they won\u2019t need to pause hormonal treatment if they wish to have children. An <\/span><a href=\"https:\/\/www.jahonline.org\/article\/S1054-139X(16)30958-2\/fulltext\"><span style=\"font-weight: 400;\">estimated<\/span><\/a><span style=\"font-weight: 400;\"> three percent of transgender adolescents use fertility preservation before beginning gender-affirming therapies. This is also a popular fertility preservation option for people undergoing <\/span><a href=\"https:\/\/www.edrugstore.com\/blog\/current-health-news\/fertility-preservation-options-for-male-cancer-patients\/\"><span style=\"font-weight: 400;\">cancer treatment<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Microsurgical testicular sperm extraction (microTESE).<\/b><span style=\"font-weight: 400;\"> The microTESE procedure allows semen to be extracted directly from the testes. Samples are analyzed and frozen for future use, if the sperm is viable.<\/span><\/li>\n<\/ul>\n<h4>ESSM Is a New Option<\/h4>\n<p><span style=\"font-weight: 400;\">You have to undergo semen analysis to find out your sperm count and to learn more about the quality of your sperm. With traditional semen analysis, many people find that they have <\/span><a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/your-sperm-may-be-endangered-heres-what-you-can-do-about-it\/\"><span style=\"font-weight: 400;\">low sperm counts<\/span><\/a><span style=\"font-weight: 400;\">. Some people are told that they have no sperm, which is also referred to as azoospermia.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">With the ESSM process, providers are able to find and freeze sperm in people with low sperm counts, including people with azoospermia. The limited fertility options available make the ESSM procedure an attractive new option for transgender women undergoing gender-affirming care.\u00a0<\/span><\/p>\n<h3>How ESSM Works<\/h3>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/2.jpeg-41_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34067\" title=\"Sperm collection cup\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/2.jpeg-41_11zon.jpg\" alt=\"Sperm collection cup\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/2.jpeg-41_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/2.jpeg-41_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">ESSM is an advanced semen evaluation and processing technique. It allows providers to effectively locate and freeze sperm in the semen of people with low sperm counts. It\u2019s exclusively performed by <\/span><a href=\"https:\/\/www.mazelabs.com\/male-infertility\/extended-sperm-search-microfreeze-essm\/\"><span style=\"font-weight: 400;\">Maze<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h4>The ESSM Process<\/h4>\n<p><span style=\"font-weight: 400;\">The ESSM process differs from standard semen analysis. Steps include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Sampling. <\/b><span style=\"font-weight: 400;\">First, a person provides a semen sample, as they would for a standard semen analysis.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Processing.<\/b><span style=\"font-weight: 400;\"> The team processes the sample, dividing the entire semen sample into five microliter droplets.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Scanning. <\/b><span style=\"font-weight: 400;\">The team spends several hours carefully scanning the droplets using a high-powered microscope. This allows them to identify sperm that may have been missed during standard semen analysis.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>SpermVD.<\/b><span style=\"font-weight: 400;\"> The sperm are then placed on a device, called <\/span><a href=\"https:\/\/academic.oup.com\/humrep\/article\/33\/11\/1975\/5115483?login=false\"><span style=\"font-weight: 400;\">SpermVD<\/span><\/a><span style=\"font-weight: 400;\">. This specialized device allows individual sperm to be transferred to a microdroplet prior to freezing.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cryopreservation. <\/b><span style=\"font-weight: 400;\">The sperm are frozen in a small quantity of fluid for later use by a process called intracytoplasmic sperm injection (ICSI-IVF).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Injection.<\/b><span style=\"font-weight: 400;\"> Sperm are thawed for injection into an egg (ICSI-IVF).\u00a0<\/span><\/li>\n<\/ul>\n<h3>Advantages of ESSM<\/h3>\n<p><span style=\"font-weight: 400;\">ESSM may open doors for people who haven\u2019t had success with traditional semen analysis and preservation techniques.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Advantages of ESSM include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Efficient process. <\/b><span style=\"font-weight: 400;\">ESSM allows providers to find more sperm than standard semen collection can. The process also allows for quicker identification of sperm, which means it can be used as soon as eggs are available, improving rates of fertilization.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Strong results.<\/b><span style=\"font-weight: 400;\"> ESSM has had <\/span><a href=\"https:\/\/www.mazelabs.com\/male-infertility\/extended-sperm-search-microfreeze-essm\/\"><span style=\"font-weight: 400;\">promising results<\/span><\/a><span style=\"font-weight: 400;\"> in people with low sperm counts. In fact, recent findings show that ESSM was successful in finding and freezing sperm in 44 percent of men with azoospermia.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Sperm survival.<\/b><span style=\"font-weight: 400;\"> Over 90 percent of sperm survive the freezing and thawing process.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Less invasive.<\/b><span style=\"font-weight: 400;\"> ESSM is less invasive than the microTESE procedure; it only involves ejaculating into a specimen collection cup and doesn\u2019t carry risk for damage to the testes. Some people also find the microTESE procedure to be painful.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Though it was produced as a fertility option for men with low sperm counts, ESSM could benefit transgender women as well. ESSM provides transgender women with improved odds of finding viable sperm to preserve as well as a less-invasive option than microTESE.<\/span><\/p>\n<h3>Disadvantages of ESSM<\/h3>\n<p><span style=\"font-weight: 400;\">ESSM is still considered a new procedure. Additional research is needed to identify potential benefits and disadvantages for its use in transgender women.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Current disadvantages of ESSM include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>High costs.<\/b><span style=\"font-weight: 400;\"> Fertility preservation can be expensive. Clients must pay for the collection, freezing, and storage of their sperm.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Risk of decreased sperm viability. <\/b><span style=\"font-weight: 400;\">All fertility preservation comes with the risk of reduced sperm viability during the freezing and thawing process.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Potential increased risk for miscarriage. <\/b><span style=\"font-weight: 400;\">Couples using sperm from both traditional cryopreservation and the ESSM process may have a higher risk of miscarriage.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Testosterone production. <\/b><span style=\"font-weight: 400;\">ESSM requires consistent testosterone production.\u00a0<\/span><\/li>\n<\/ul>\n<h3>Conclusion<\/h3>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/3.jpeg-38_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34068\" title=\"spermatozoids\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/3.jpeg-38_11zon.jpg\" alt=\"spermatozoids\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/3.jpeg-38_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2023\/01\/3.jpeg-38_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Transgender women face unique fertility challenges. Many transgender women do not use fertility preservation prior to beginning gender-affirming care.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The new ESSM procedure shows promise as a fertility option for transgender women. It\u2019s less invasive than the TESE procedure and is successful in retrieving viable sperm from people with low sperm counts. Sperm retrieval is possible with ESSM unless sperm production has stopped completely.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Current research on fertility in transgender people is limited. Fortunately, fertility options are available, and research continues to grow. Finding a knowledgeable and friendly healthcare provider can help you to get the fertility treatment you need to start your family.<\/span><\/p>\n<h3>Explore Your Sexual Health and Fertility Options with eDrugstore<\/h3>\n<p><span style=\"font-weight: 400;\">We\u2019re here to support you in finding reliable information and evidence-based treatment for happier and healthier relationships. Follow our blog for up-to-date, evidence-based information about intimacy, relationships, <\/span><a href=\"https:\/\/www.edrugstore.com\/erectile-dysfunction\/?__mscta=2392_89584_11488\"><span style=\"font-weight: 400;\">erectile dysfunction<\/span><\/a><span style=\"font-weight: 400;\">, premature ejaculation, and other sexual health topics. Make eDrugstore your source for information you can trust.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Highlights\u00a0 Transgender women often struggle with fertility issues as a result of long-term hormonal therapies. Fertility options for transgender women include \u201cnatural\u201d conception, sperm cryopreservation, and microsurgical testicular sperm extraction (microTESE). The extended sperm search and microfreeze (ESSM) procedure allows providers to find and preserve sperm in people with low sperm counts who were unsuccessful [&hellip;]<\/p>\n","protected":false},"author":13,"featured_media":34066,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[18],"tags":[],"class_list":["post-34065","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-current-health-news"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Transgender women often experience infertility. Learn about a new sperm retrieval procedure that may be a new fertility option for transgender women.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Shelby Graves\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.edrugstore.com\/blog\/current-health-news\/essm-fertility-option-for-transgender-women\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO Pro (AIOSEO) 4.9.10\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Online Prescription Medications | eDrugstore Online Pharmacy Over 4 Million Prescriptions Lifestyle Medications\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"ESSM: A New Fertility Option for Transgender Women? | Online Prescription Medications\" \/>\n\t\t<meta property=\"og:description\" content=\"Transgender women often experience infertility. 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