{"id":31874,"date":"2024-01-17T02:55:39","date_gmt":"2024-01-16T19:55:39","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=31874"},"modified":"2024-09-09T10:46:58","modified_gmt":"2024-09-09T03:46:58","slug":"can-high-cholesterol-cause-hair-loss","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/hair-growth\/can-high-cholesterol-cause-hair-loss\/","title":{"rendered":"Can High Cholesterol Cause Hair Loss?"},"content":{"rendered":"<p><b>Highlights\u00a0\u00a0<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Cholesterol supports cellular function on many levels.<\/strong><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Scientists have long known that abnormal cholesterol levels can cause hair loss.<\/strong><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Drugs that affect cholesterol levels may cause hair loss in some patients.<\/strong><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>There is hope that someday we may be able to restore hair by optimizing cholesterol levels.<\/strong><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>If you\u2019re concerned about your cholesterol levels, try an at-home testing kit.<\/strong><\/li>\n<\/ul>\n<hr \/>\n<p><b><\/b><\/p>\n<p><span style=\"font-weight: 400;\">The only obvious connection between high cholesterol and hair loss is that they\u2019re both age-related conditions. <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.13993\"><span style=\"font-weight: 400;\">Researchers suspect<\/span><\/a><span style=\"font-weight: 400;\">, however, that high cholesterol may play a role in balding. Science does not yet understand how high cholesterol can cause hair loss, but it\u2019s becoming more apparent that there is a connection.<\/span><\/p>\n<h3>The Role of Cholesterol in the Body<\/h3>\n<p><span style=\"font-weight: 400;\">Cholesterol has earned a bad reputation in popular culture. You have most likely learned about the existence of this \u201cevil\u201d compound through the complaints of your elders.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Far from being a net negative, cholesterol plays an important role in our bodies. Here\u2019s why:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Living tissue cannot exist without cholesterol.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cholesterol is an essential component of our cell membranes.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It plays an essential role in many biochemical processes.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It forms a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2674689\/\"><span style=\"font-weight: 400;\">barrier<\/span><\/a><span style=\"font-weight: 400;\"> on our skin, protecting us from external chemicals and toxins.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It serves as insulation, called <\/span><a href=\"https:\/\/medlineplus.gov\/ency\/article\/002261.htm#:~:text=Myelin%20is%20an%20insulating%20layer,efficiently%20along%20the%20nerve%20cells.\"><span style=\"font-weight: 400;\">myelin<\/span><\/a><span style=\"font-weight: 400;\">, around nerves, essential for rapid nerve conduction.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Our bodies use it to make hormones.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It plays a role in defining the color of our skin.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">When you hear someone complaining about high cholesterol, that person has elevated levels of \u201cbad\u201d (or \u201clousy\u201d) cholesterol \u2014 low-density lipoprotein (LDL). LDL is the form of cholesterol that clings to the walls of your arteries and accumulates over time. Eventually, the buildup can clog your arteries, leading to life-threatening health problems.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">High-density lipoprotein cleans up the cholesterol from your arteries, taking it back to your liver. HDL cholesterol is, therefore, the \u201cgood\u201d (or \u201chealthy\u201d) cholesterol. When available in sufficient amounts, HDL cholesterol protects you from disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The worst cholesterol combination you can have is high LDL and low HDL. The best combination is low LDL and high HDL.<\/span><\/p>\n<h3>Cholesterol and Hair Growth\/Loss<\/h3>\n<p><span style=\"font-weight: 400;\">Scientists don\u2019t yet understand how cholesterol affects hair growth, but they know that a connection exists between high cholesterol and male-pattern hair loss.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">We have long known that if you are bald or balding, you are more likely to suffer from heart disease. Now researchers have <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27717019\/\"><span style=\"font-weight: 400;\">figured out<\/span><\/a><span style=\"font-weight: 400;\"> that if you suffer from hair loss, you are more likely to have abnormal cholesterol levels as well. The two are somehow connected.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Abnormal lipid levels are in some ways involved in hypertrichosis (abnormally abundant hair growth on the face and other normally hairless areas). When your cholesterol is out of control, it may also contribute to scarring and permanent hair loss.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though there\u2019s much more to learn, scientists already understand some of the pathways through which cholesterol could theoretically affect hair growth.<\/span><\/p>\n<h3>How Can High Cholesterol Cause Hair Loss?<\/h3>\n<p>In addition to being a building block of our cell membranes, cholesterol also regulates cell signaling. It plays a part in biochemical processes that have a significant impact on hair growth.<\/p>\n<p><span style=\"background-color: var(--bs-body-bg); color: var(--bs-body-color); font-family: var(--bs-body-font-family); font-size: var(--bs-body-font-size); text-align: var(--bs-body-text-align);\">These processes involve:<\/span><\/p>\n<ul>\n<li><b style=\"background-color: var(--bs-body-bg); color: var(--bs-body-color); font-family: var(--bs-body-font-family); font-size: var(--bs-body-font-size); text-align: var(--bs-body-text-align);\">The hedgehog protein.<\/b><span style=\"font-weight: 400;\"> Cholesterol determines how much or how little hedgehog protein our body creates. The role of the <\/span><a style=\"font-weight: bold; background-color: var(--bs-body-bg); font-family: var(--bs-body-font-family); font-size: var(--bs-body-font-size); text-align: var(--bs-body-text-align);\" href=\"https:\/\/www.edrugstore.com\/blog\/hair-loss\/what-does-the-sonic-hedgehog-gene-do-for-hair-loss\/\"><span style=\"font-weight: 400;\">hedgehog protein<\/span><\/a><span style=\"font-weight: 400;\"> in the body is complex, but suffice it to say that a shortage of this biochemical compound <\/span><a style=\"font-weight: bold; background-color: var(--bs-body-bg); font-family: var(--bs-body-font-family); font-size: var(--bs-body-font-size); text-align: var(--bs-body-text-align);\" href=\"https:\/\/biomeddermatol.biomedcentral.com\/articles\/10.1186\/s41702-019-0047-x\"><span style=\"font-weight: 400;\">may result<\/span><\/a><span style=\"font-weight: 400;\"> in hair loss.<\/span><\/li>\n<li><b>Wnt signaling.<\/b><span style=\"font-weight: 400;\"> Cholesterol can turn Wnt signaling on and off. Wnt signaling plays a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC316619\/\"><span style=\"font-weight: 400;\">crucial role<\/span><\/a><span style=\"font-weight: 400;\"> in hair growth and preventing hair graying. Researchers have even considered it as a possible pathway for fighting male-pattern baldness.<\/span><\/li>\n<li><b>The sebaceous gland. <\/b><span style=\"font-weight: 400;\">It would not be farfetched to assume that cholesterol can affect the functioning of the oil glands in our scalp. These tiny lipid-rich organs produce more oil in the balding areas of the scalp. Often, an <\/span><a href=\"https:\/\/www.edrugstore.com\/blog\/hair-loss\/is-there-a-link-between-hair-loss-and-erectile-dysfunction\/\"><span style=\"font-weight: 400;\">oily scalp<\/span><\/a><span style=\"font-weight: 400;\"> is the first sign of balding. In many hair-loss cases, abnormal oil production persists after the complete loss of hair.<\/span><\/li>\n<li><b>Cholesterol synthesis.<\/b><span style=\"font-weight: 400;\"> Altered cholesterol synthesis in the scalp tissue surrounding the hair follicles <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.13993\"><span style=\"font-weight: 400;\">can lead<\/span><\/a><span style=\"font-weight: 400;\"> to scarring alopecia.<\/span><\/li>\n<li><b>Glycerol kinase 5.<\/b><span style=\"font-weight: 400;\"> This compound regulates cholesterol synthesis in the skin. When it suffers a disruption, it can lead to lipid accumulation in the skin and <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5495269\/\"><span style=\"font-weight: 400;\">gradual hair loss<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<\/ul>\n<figure id=\"attachment_34628\" aria-describedby=\"caption-attachment-34628\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/2.jpeg-96_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-34628\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/2.jpeg-96_11zon.jpg\" alt=\"Healthy and oily hair graphic\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/2.jpeg-96_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/2.jpeg-96_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><figcaption id=\"caption-attachment-34628\" class=\"wp-caption-text\"><em>Cholesterol may be responsible for oily hair.<\/em><\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">These cellular signaling pathways are only a few of the many pathways that regulate hair growth and cycling. Cholesterol is involved in many more of them. It affects a type of protein that can delay stem cell activity in the hair bulb. It can delay the anagen(growth) phase of the hair cycle and extend the telogen (resting) phase.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The bottom line? High cholesterol can cause hair loss in more ways than science can currently comprehend.<\/span><\/p>\n<h3>Can High Cholesterol Cause Alopecia Areata?<\/h3>\n<p><span style=\"font-weight: 400;\">Cholesterol <\/span><a href=\"https:\/\/epicure.cumc.columbia.edu\/sites\/default\/files\/content\/epiCURE%20Publications\/Lim%20CP%20et%20al%202018%20Big%20Data%20Reveal%20Insights%20into%20AA%20Comorbidities.pdf\"><span style=\"font-weight: 400;\">is involved<\/span><\/a><span style=\"font-weight: 400;\"> in inflammation, autoimmune responses, and hair disorders. And <\/span><a href=\"https:\/\/www.jidsponline.org\/article\/S1087-0024(17)30046-1\/fulltext\"><span style=\"font-weight: 400;\">it looks like<\/span><\/a><span style=\"font-weight: 400;\"> statins, drugs that lower bad cholesterol levels, may treat <\/span><a href=\"https:\/\/www.edrugstore.com\/blog\/hair-loss\/what-causes-male-balding-and-what-can-be-done-about-it\/\"><span style=\"font-weight: 400;\">alopecia areata<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Doctors used a combination of simvastatin and ezetimibe to treat alopecia areata and prevent flare-ups of the disease. In addition to lowering cholesterol levels, some statins also modulate immune responses.<\/span><\/p>\n<h3>Can Low Cholesterol Cause Hair Loss?<\/h3>\n<p><span style=\"font-weight: 400;\">High levels of LDL cholesterol can cause hair loss in many ways. Evidence shows that low HDL cholesterol can have similar effects. <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjd.14529\"><span style=\"font-weight: 400;\">A study<\/span><\/a><span style=\"font-weight: 400;\"> performed on middle-aged women found a link between low HDL cholesterol and hair loss.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Granted, men experience hair loss differently than women, but the results are still interesting. If we consider that testosterone <\/span><a href=\"https:\/\/www.sciencedaily.com\/releases\/2015\/03\/150308091404.htm\"><span style=\"font-weight: 400;\">may lower<\/span><\/a><span style=\"font-weight: 400;\"> HDL cholesterol levels in men aged 20-50, cholesterol starts to make even more sense as a reason for hair loss.<\/span><\/p>\n<h3>Does Cholesterol Medicine Cause Hair Loss?<\/h3>\n<p><span style=\"font-weight: 400;\">Cholesterol plays many roles in hair growth and loss. Therefore, it is hardly surprising that drug therapies that target cholesterol can have devastating effects on your hair. Some of these drugs can make your hair fall out. Others can grow hair where you don\u2019t want to have any.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Doctors are aware that statins, a class of cholesterol-lowering drugs, can cause hair loss as a side effect. Statins exert their action in the liver, blocking an enzyme the liver uses to make cholesterol.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Only about one percent of patients using statins have complained about losing hair, and we don\u2019t yet understand how these drugs make hair fall out. To further complicate the cholesterol-hair loss link, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5705358\/\"><span style=\"font-weight: 400;\">researchers used simvastatin<\/span><\/a><span style=\"font-weight: 400;\">, a popular cholesterol-lowering drug, to regrow hair in some alopecia areata patients.<\/span><\/p>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/3.jpeg-92_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34629\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/3.jpeg-92_11zon.jpg\" alt=\"Bottle of Simvastatin pills\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/3.jpeg-92_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/3.jpeg-92_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>While some statins help alopecia patients recover hair, others may cause hair loss. Researchers have <a href=\"https:\/\/www.amjmed.com\/article\/S0002-9343(02)01135-X\/fulltext\">established links<\/a> between atorvastatin and hair loss. For now, however, despite a handful of case studies, this link between atorvastatin and hair loss is tenuous.<\/p>\n<h3>Can We Reverse High Cholesterol and Hair Loss?<\/h3>\n<p><span style=\"font-weight: 400;\">We can manipulate our cholesterol levels to some degree through diet. We can eat foods that help raise HDL cholesterol levels and lower LDL cholesterol levels. We can avoid foods that spike LDL cholesterol.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">By altering our cholesterol balance, we should be able to reverse some of the ill effects of abnormal cholesterol.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In a <\/span><a href=\"https:\/\/www.nature.com\/articles\/s41598-018-28663-9\"><span style=\"font-weight: 400;\">2018 study<\/span><\/a><span style=\"font-weight: 400;\">, Johns Hopkins\u2019 researchers fed mice a cholesterol-rich Western diet. In response, the majority of the test animals began losing hair.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The scientist then fed the mice a compound that <\/span><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/atvbaha.109.201673\"><span style=\"font-weight: 400;\">interfered<\/span><\/a><span style=\"font-weight: 400;\"> with the formation of cholesterol. They successfully reversed some of the damage the unbalanced diet had caused to the hair of the test animals.<\/span><\/p>\n<h3>A Final Word<\/h3>\n<p><span style=\"font-weight: 400;\">Although we don\u2019t understand how cholesterol impacts hair growth, we can answer the question, \u201cCan high cholesterol cause hair loss?\u201d with reasonable certainty. It can, and it does.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So watch what you eat. Keeping your cholesterol levels in check can save your life and that mop on top of your noggin as a bonus.<\/span><\/p>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/4.jpeg-45_11zon.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34630\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/4.jpeg-45_11zon.jpg\" alt=\"Low cholesterol diet\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/4.jpeg-45_11zon.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2022\/02\/4.jpeg-45_11zon-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Scientists may one day develop a solution that allows humans to reverse the damage of high cholesterol and restore hair. Until then, you can turn to FDA-approved solutions that already exist, like <\/span><a href=\"https:\/\/www.edrugstore.com\/propecia\/\"><span style=\"font-weight: 400;\">Propecia<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.edrugstore.com\/finasteride\/\"><span style=\"font-weight: 400;\">finasteride<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019re concerned about your cholesterol levels, consider a <\/span><a href=\"https:\/\/www.edrugstore.com\/test-kits\/cholesterol-lipids-test-kit\/\"><span style=\"font-weight: 400;\">cholesterol and lipids test kit<\/span><\/a><span style=\"font-weight: 400;\"> that allows you to safely check your cholesterol at home.<\/span><\/p>\n<h3>eDrugstore Can Help You Keep Your Hair<\/h3>\n<p><span style=\"font-weight: 400;\">With eDrugstore, you get a complimentary consultation with a U.S.-licensed doctor who can provide you with the prescriptions you need. We will deliver your order quickly and discreetly, and we\u2019ll ship it for free. Check out our FDA-approved <\/span><a href=\"https:\/\/www.edrugstore.com\/hair-loss\/?__mscta=2809_90772_11584\"><span style=\"font-weight: 400;\">hair restoration medications<\/span><\/a><span style=\"font-weight: 400;\"> today.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cholesterol modulates hair growth in more ways than we currently understand. How can cholesterol cause hair loss? Find out how it may impact your hair.<\/p>\n","protected":false},"author":22,"featured_media":34631,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[80],"tags":[],"class_list":["post-31874","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hair-growth"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Cholesterol modulates hair growth in more ways than we currently understand. How can cholesterol cause hair loss? 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