{"id":28869,"date":"2020-04-30T17:00:18","date_gmt":"2020-04-30T17:00:18","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=28869"},"modified":"2026-03-31T04:57:56","modified_gmt":"2026-03-30T21:57:56","slug":"sildenafil-cream-for-women-ready-for-phase-2-clinical-trials","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/sex-health\/sildenafil-cream-for-women-ready-for-phase-2-clinical-trials\/","title":{"rendered":"Sildenafil Cream for Women Ready for Phase 2 Clinical Trials"},"content":{"rendered":"<p>Sildenafil is the active ingredient in Viagra, the wildly popular pill used to treat erectile dysfunction (ED) in men. It is effective in temporarily improving men\u2019s inability to get or maintain an erection hard enough for sexual intercourse, as well as their low sexual desire, or low libido.<\/p>\n<p>However, men are not alone in their sexual dysfunctions. <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/female-sexual-dysfunction\/symptoms-causes\/syc-20372549\">Female sexual dysfunction (FSD)<\/a> is described as \u201cpersistent, recurrent problems with sexual response, desire, orgasm or pain \u2014 that distress you or strain your relationship with your partner.\u201d It is estimated that <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/9121-sexual-dysfunction\">close to half of all women<\/a> report experiencing some type of sexual dysfunction at some point in their lives.<\/p>\n<h3>Female Sexual Dysfunction Can Include:<\/h3>\n<ul>\n<li>Low sexual desire<\/li>\n<li>Sexual arousal disorder<\/li>\n<li>Orgasmic disorder<\/li>\n<li>Sexual pain disorder<\/li>\n<\/ul>\n<p>While women experience sexual dysfunction at similar if not greater rates than men, their treatment options are far inferior. Hopefully, that will soon change, as a new medication is about to enter Phase 2 of the FDA\u2019s required trials to get treatments on the market.<\/p>\n<h3>Sildenafil Cream: A Non-Pill and Noninvasive Alternative for Women<\/h3>\n<p><strong><img decoding=\"async\" class=\"fr-fil fr-dib aligncenter\" style=\"width: 600px;\" src=\"https:\/\/www.mediashower.com\/img\/783C9ED0-73D1-11EA-A15E-81ABF83ACE25\/bigstock-Set-Of-White-Bottles-For-Liqui-307911715_900x.jpg\" alt=\"Unlabeled products.\" width=\"600\" \/><\/strong><\/p>\n<p><a href=\"https:\/\/darebioscience.com\/pipeline\/sildenafil-cream\/\">Dar\u00e9 Bioscience<\/a> is the latest company to propose a treatment for FSD. What makes its treatment different, however, is that the medication is a cream instead of a <a href=\"https:\/\/www.healthgrades.com\/right-care\/sexual-health\/pros-and-cons-of-the-little-pink-pill-for-women\">pill<\/a> or an <a href=\"https:\/\/www.reliasmedia.com\/articles\/144777-bremelanotide-injection-vyleesi\">injection<\/a>. The cream would work in a similar way to Viagra. Women would apply it to their genital tissue, which would increase blood flow in that localized area, ideally increasing women\u2019s overall sexual experience.<\/p>\n<p>If approved by the FDA, Dare\u2019s product would be the first medication approved to specifically treat female sexual arousal disorder (FSAD). The <a href=\"https:\/\/www.globenewswire.com\/news-release\/2019\/06\/17\/1869546\/0\/en\/Dar%C3%A9-Bioscience-Inc-Announces-Positive-Results-in-Thermography-Feasibility-Study-with-Sildenafil-Cream-3-6-a-Potential-Therapy-for-Female-Sexual-Arousal-Disorder.html\">initial testing results<\/a> are promising. Though tested amongst a small sample of six women, all participants experienced significant increases in genital temperature after applying the cream, suggesting an increase in genital blood flow. So, what\u2019s next for the treatment?<\/p>\n<h3>Passing FDA Standards<\/h3>\n<p>Dare\u2019s sildenafil cream passed the FDA\u2019s first phase of clinical trials, meaning that an appropriate dosage was determined for the medication. Now, the drug moves into Phase 2 of testing. In Phase 2, the cream will be tested in a much larger sample of participants, likely a few hundred people. To continue on to Phase 3, the cream must be determined to be as effective as or more effective than similar drugs used to combat female sexual dysfunction.<\/p>\n<h3>Hope for Women on the Horizon<\/h3>\n<p><strong><img decoding=\"async\" class=\"fr-fil fr-dib aligncenter\" style=\"width: 600px;\" src=\"https:\/\/www.mediashower.com\/img\/783C9ED0-73D1-11EA-A15E-81ABF83ACE25\/bigstock-Shy-black-girl-lying-on-bed-un-324970981_900x.jpg\" alt=\"Smiling woman lying down.\" width=\"600\" \/><\/strong><\/p>\n<p>With Dare Bioscience\u2019s Sildenafil cream, treatments for female sexual dysfunction just got a lot more exciting. The cream has the promise to be a great alternative to existing options <a href=\"http:\/\/blog.edrugstore.com\/erectile-dysfunction\/viagra\/why-experimental-drug-is-closer-to-being-viagra-for-women\/\">already available<\/a> on the market. For instance, the cream is a much less painful option than <a href=\"https:\/\/www.reliasmedia.com\/articles\/144777-bremelanotide-injection-vyleesi\">Vyleesi<\/a>, which requires women to inject themselves with medication 45 minutes before sexual activity is to occur. Another benefit of the cream is that it doesn\u2019t require a daily application to be effective, unlike <a href=\"https:\/\/www.healthgrades.com\/right-care\/sexual-health\/pros-and-cons-of-the-little-pink-pill-for-women\">Addyi<\/a>, which requires women to take a pill daily.<\/p>\n<p>Regardless of the Sildenafil cream\u2019s outcome in clinical trials, it is clear that women need better alternatives to treat sexual dysfunction. Hopefully, this is just the start of noninvasive, promising options for women.<\/p>\n<p><!-- Media Shower Impressions --><\/p>\n<div class=\"ms_article_id\" style=\"display: none;\" data-ms-article-id=\"81720\"><\/div>\n<p><!-- \/Media Shower Impressions --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sildenafil is the active ingredient in Viagra, the wildly popular pill used to treat erectile dysfunction (ED) in men. It is effective in temporarily improving men\u2019s inability to get or maintain an erection hard enough for sexual intercourse, as well as their low sexual desire, or low libido. However, men are not alone in their [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":28871,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[1926],"tags":[],"class_list":["post-28869","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sex-health"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"While women experience sexual dysfunction at similar if not greater rates than men, their treatment options are far inferior. 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