{"id":251,"date":"2023-10-02T08:00:00","date_gmt":"2023-10-02T01:00:00","guid":{"rendered":"http:\/\/edrugstore.uat.com\/articles\/?p=251"},"modified":"2024-06-05T21:02:44","modified_gmt":"2024-06-05T14:02:44","slug":"can-you-take-cialis-and-viagra-together","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/can-you-take-cialis-and-viagra-together\/","title":{"rendered":"Can You Take Cialis and Viagra Together?"},"content":{"rendered":"<p><b>Highlights\u00a0<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><b>Can you take Cialis and Viagra together? The short answer is no. While Viagra and Cialis are effective separately, they shouldn\u2019t be taken together.<\/b><\/li>\n<li aria-level=\"1\"><b>Taking two different ED drugs at the same time elevates your risks of side effects, including hypotension, visual disturbances, and priapism.<\/b><\/li>\n<li aria-level=\"1\"><b>Always follow the instructions on the bottle. If a drug doesn\u2019t seem to be working, speak with your doctor.<\/b><\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.edrugstore.com\/blog\/espanol\/puedes-tomar-cialis-y-viagra-al-mismo-tiempo\"><span style=\"font-weight: 400;\">[<\/span><span style=\"font-weight: 400;\">Espa\u00f1ol<\/span><span style=\"font-weight: 400;\">]<\/span><\/a><\/p>\n<hr \/>\n<div style=\"width: 900px; margin-right: auto; margin-left: auto;\">\n<div class=\"epyt-video-wrapper\"><iframe loading=\"lazy\"  id=\"_ytid_22876\"  width=\"1260\" height=\"708\"  data-origwidth=\"1260\" data-origheight=\"708\" src=\"https:\/\/www.youtube.com\/embed\/V0gZUQHd3IQ?enablejsapi=1&#038;autoplay=0&#038;cc_load_policy=0&#038;cc_lang_pref=&#038;iv_load_policy=1&#038;loop=0&#038;rel=0&#038;fs=1&#038;playsinline=0&#038;autohide=2&#038;theme=dark&#038;color=red&#038;controls=1&#038;disablekb=0&#038;\" class=\"__youtube_prefs__  epyt-is-override  no-lazyload\" title=\"YouTube player\"  allow=\"fullscreen; accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen data-no-lazy=\"1\" data-skipgform_ajax_framebjll=\"\"><\/iframe><\/div>\n<\/div>\n\n<p><span style=\"font-weight: 400;\">Cialis and Viagra are so effective at treating the symptoms of <\/span><a href=\"https:\/\/www.edrugstore.com\/erectile-dysfunction\/?__mscta=2392_84438_12550\"><span style=\"font-weight: 400;\">erectile dysfunction<\/span><\/a><span style=\"font-weight: 400;\">, it\u2019s easy to get carried away and wonder if you\u2019d get even more benefit by taking them together.\u00a0<\/span><\/p>\n<p><b>Don\u2019t. <\/b><span style=\"font-weight: 400;\">Taking Cialis and Viagra together is a bad idea and not worth the risk. Instead, choose one or the other, or consult with one of our online doctors to see which one is best for you.<\/span><\/p>\n<h3>How Do Cialis and Viagra Work?<\/h3>\n<p><span style=\"font-weight: 400;\">All oral erectile dysfunction medications block an enzyme called phosphodiesterase-5 (PDE5), which increases blood flow to the penis and results in a harder, longer-lasting erection. To understand how this relates to taking Cialis and Viagra together, it helps to know the basics of how erections happen.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When men get sexually aroused, the nerves near the penis release nitric oxide. Nitric oxide is a chemical signal that tells the cells in the blood vessels of the penis to make more of a substance called cyclic guanosine monophosphate, or cGMP. cGMP makes the blood vessels relax and open up so more blood flows into the penis to make it rigid.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When a guy isn\u2019t aroused anymore, PDE5 acts like a molecular clean-up crew by breaking down the cGMP, which lets blood flow out of the penis so it becomes flaccid again.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In men with ED, the initial arousal signal doesn\u2019t generate enough cGMP to make the penis fully hard and keep it that way long enough to have sex. By blocking PDE5, drugs like Viagra slow the breakdown of cGMP so enough of it accumulates to produce an erection.<\/span><\/p>\n<h3>There\u2019s No Benefit to Taking Cialis and Viagra Together<\/h3>\n<p><span style=\"font-weight: 400;\">Before we even touch on the possible health risks, you should know that taking Viagra and Cialis together isn\u2019t going to give the double-boost you think it will. We mention this first just in case safety issues aren\u2019t enough to deter you from trying!<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Viagra and Cialis molecules interfere with PDE5 because they\u2019re shaped like cGMP, one of the molecules that binds with PDE5 receptor sites. These drugs are even better at attaching to the receptors than cGMP, and they compete against each other for the open binding sites on the enzyme. Once it\u2019s in place, Viagra won\u2019t budge, and every site taken up by Viagra or Cialis is one that can\u2019t bind to cGMP to break it down.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Since there are a limited number of sites, and once all available ones are filled, taking more Viagra isn\u2019t going to have any additional effect. There\u2019s simply no room; it\u2019s already too crowded!<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"fr-fil fr-dib fr-draggable aligncenter\" src=\"https:\/\/www.mediashower.com\/img\/666B8A9A-FA04-11EA-85A2-2B07AA396CD2\/bigstock-Measuring-The-Size-Of-A-Banana-361163290_900x.jpg\" alt=\"Measuring a banana.\" width=\"900\" height=\"600\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Because both drugs target the same enzyme, taking both together would be similar to taking an overdose of only one of them. Whether occupied by Viagra or Cialis, there\u2019s a point where all the enzyme receptor sites are saturated, and any extra drug gets carried around your body waiting to be broken down by the liver.<\/span><\/p>\n<h3>Is It Safe To Take Viagra and Cialis Together?<\/h3>\n<p><b>No, it\u2019s not safe to pair these drugs.<\/b><span style=\"font-weight: 400;\"> PDE5 isn\u2019t only found in the penis; it\u2019s just one of many types of phosphodiesterases. This is where the health risk part comes in.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Phosphodiesterases are a big family of enzymes that break down messenger chemicals like cGMP. They\u2019re used all over the body to give instructions to nearby cells and tissues. Since PDE5i drugs are so similar to cGMP, they can bind to PDE5 found in locations besides the penis, like the retina, large intestine, and blood vessels.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although ED drugs prefer binding to PDE5, they can also bind to other PDE types. The more excess Viagra in your system, the more likely it is to run into and attach to other PDE enzymes. This unintended activity is thought to be the cause of the most frequently reported side effects of ED drugs: headache, dizziness, temporary visual changes, muscle pain, and stomach upset.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Just like taking too much Viagra by itself, adding a normal dose of Cialis to a normal dose of Viagra increases your chances of side effects due to too much of a good thing. This includes a greater risk of visual disturbances, headache, very low blood pressure, and an otherwise rare side effect called priapism, which is a painful erection that doesn\u2019t go away on its own, even when you aren\u2019t sexually stimulated.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You\u2019ve heard the commercials telling you, \u201cContact your doctor immediately if you have an erection lasting longer than four hours,\u201d right? That\u2019s mentioned separately from the rest of the side effects because priapism <\/span><a href=\"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/viagra\/warning-about-erection-lasting-longer-than-4-hours-is-no-joke\/\"><span style=\"font-weight: 400;\">can be a medical emergency<\/span><\/a><span style=\"font-weight: 400;\"> that needs swift treatment to prevent serious damage to the penis. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">After four hours, the blood trapped in the erect penis has barely any oxygen left, and unless it\u2019s drained right away so new blood can enter, the cells in the erectile tissue will start to die.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If the idea of inadvertently crippling your penis doesn\u2019t make you think twice about taking Viagra and Cialis together, here\u2019s a spoiler alert: it\u2019s pretty horrible.<\/span><\/p>\n<h3>What To Do If Your ED Medication Isn\u2019t Working<\/h3>\n<p><span style=\"font-weight: 400;\">While PDE5 inhibitors are very effective for erectile dysfunction, our bodies are all different and respond to drugs differently. If you\u2019re taking the max dose of your prescribed ED drug and still aren\u2019t experiencing the hoped-for effects, talk with your doctor about trying a different ED drug.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"fr-fil fr-dib fr-draggable aligncenter\" src=\"https:\/\/www.mediashower.com\/img\/666B8A9A-FA04-11EA-85A2-2B07AA396CD2\/bigstock-Long-Cactus-With-Blurred-Cactu-369670255_900x.jpg\" alt=\"Rows of cactus plants.\" width=\"900\" height=\"600\" \/><\/p>\n<p><span style=\"font-weight: 400;\">You can take them all for a test drive if your doctor approves, but just like with cars, you can only test drive one at a time, not to mention \u201cyour mileage may vary.\u201d However, Viagra can be safely and effectively used in combination with ED drugs that work by a different mechanism of action, like Caverject or MUSE (Medicated Urethral System for Erections). For maximum effect, you can also combine any of the ED drugs with a male enhancement pump.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Need a more detailed rundown of what you should do when Viagra isn\u2019t doing it for you? <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2213890\/\"><span style=\"font-weight: 400;\">We\u2019ve got an article for that<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3>Benefits of Buying Viagra Online With eDrugstore<\/h3>\n<p><span style=\"font-weight: 400;\">As a leading telemedicine provider and pharmacy, eDrugstore is on a mission to make it easier for men to get treatment for erectile dysfunction and other sexual health problems. We can help you start your journey towards better sex with less stress by connecting you with a doctor from our network of U.S. -licensed physicians for a free and confidential video consultation to discuss your symptoms. If appropriate, they will even write you a prescription for treatment.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">To make the process even more convenient, your script can be filled by our pharmacy and discreetly shipped to your door.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">We\u2019ll do the heavy lifting for you, so if you\u2019re looking for harder, long-lasting erections, it\u2019s never been easier to do something about it. Visit our <\/span><a href=\"https:\/\/www.edrugstore.com\/erectile-dysfunction\/?__mscta=2392_89584_11488\"><span style=\"font-weight: 400;\">medication guide<\/span><\/a><span style=\"font-weight: 400;\"> and click Sign Up to get started today.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Can you take Cialis and Viagra together? Learn why double-dosing is a bad idea and what to do instead to safely treat your erectile dysfunction.<\/p>\n","protected":false},"author":15,"featured_media":22222,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[47,17],"tags":[],"class_list":["post-251","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cialis","category-viagra"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Can you take Cialis and Viagra together? 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