{"id":10139,"date":"2018-01-23T08:00:44","date_gmt":"2018-01-23T08:00:44","guid":{"rendered":"https:\/\/www.edrugstore.com\/blog\/?p=10139"},"modified":"2018-11-09T02:11:14","modified_gmt":"2018-11-09T02:11:14","slug":"acyclovir-vs-valtrex-which-is-better-for-shingles-outbreaks","status":"publish","type":"post","link":"https:\/\/www.edrugstore.com\/blog\/erectile-dysfunction\/acyclovir-vs-valtrex-which-is-better-for-shingles-outbreaks\/","title":{"rendered":"Acyclovir vs. Valtrex: Which is Better for Shingles Outbreaks?"},"content":{"rendered":"<p><strong><em><span class=\"dropcaps\">N<\/span>either acyclovir nor valacyclovir is a cure for shingles, an outbreak of the varicella-zoster virus in adults. Both, however, can significantly reduce the discomfort and severity of shingles symptoms.<\/em><\/strong><\/p>\n<p>Some research indicates that the winter season seems to bring with it a weakening of the body&#8217;s immune system. This, of course, makes you more vulnerable to bacterial and viral infections. In the latter category, two of the most virulent viral threats are those of influenza and the varicella-zoster virus (VZV), responsible for chickenpox in the young and shingles in older patients. And if you fall victim to the flu, it increases your risk of developing shingles.<\/p>\n<p>Fortunately, vaccines are available to reduce your chances of contracting either virus. During the 2017-18 season, flu killed more than 80,000 Americans. And while shingles is rarely a killer, it can cause untold misery in those it strikes, estimated to be one in every four Americans.<\/p>\n<p>Standard treatments for shingles include both acyclovir and Valtrex. How are these two medications alike and how are they different? Is one&#8217;s dosage schedule more convenient than the other? Can they be taken with other drugs, like flu medications?<\/p>\n<h3>What Is Shingles?<\/h3>\n<p><em>\u201cMost adults in the United States have had chickenpox, even if it was so mild as to pass unnoticed, and they are at risk for developing shingles later in life.\u201d<br \/>\n<\/em>&#8212;\u00a0<a href=\"https:\/\/www.ninds.nih.gov\/Disorders\/Patient-Caregiver-Education\/Hope-Through-Research\/Shingles-Hope-Through-Research\">The National Institute of Neurological Disorders and Stroke<\/a><\/p>\n<p>Let\u2019s review what we know about the shingles virus to date. The National Institute of Neurological Disorders and Stroke (NINDS) tell us that fully 25 percent of all adults develop the painful condition known as shingles. That\u2019s around 1 million cases that occur each year in the United States.<\/p>\n<p>As previously noted, shingles is caused by VZV, which typically manifests in childhood as chickenpox. While the red spots and itching eventually disappear, the virus does not. Instead, VZV goes deep into the nerve cell structure of the individual affected, sitting dormant, and waiting to erupt. VZV, like all viruses, is opportunistic; it manifests typically in later adulthood when many have co-morbidities or a weakened immune system.<\/p>\n<p>Other factors that could put a person at risk for developing shingles include:<\/p>\n<ul>\n<li>taking other medications that weaken the immune system, such as cancer drugs or medications for HIV\/AIDS<\/li>\n<li>physical trauma<\/li>\n<li>emotional stress<\/li>\n<li>the common cold and flu<\/li>\n<\/ul>\n<p>When shingles erupts in adulthood, it is called herpes zoster. The trigger for the disorder isn\u2019t exactly known, but it does seem to be related to stress and illness \u2013 like the flu. Herpes zoster can be an extremely painful disorder with a rash, redness, and blistering typically on one side of the face, waist, back, or chest. If shingles erupt near the eyes, patients must seek treatment from an ophthalmologist quickly or run the risk of eye infections or even loss of vision.<\/p>\n<p>In rare cases, shingles can affect the brain or spinal cord, leading to very serious and potentially life-threatening complications.<\/p>\n<p>Because the shingles virus lives in and travels up and down the nerve cells to eventually manifest on the skin, it is an extremely uncomfortable condition for adults to endure. Some of the symptoms of shingles include:<\/p>\n<ul>\n<li>nausea<\/li>\n<li>headaches<\/li>\n<li>itching<\/li>\n<li>diarrhea<\/li>\n<li>fever and chills<\/li>\n<li>tingling and skin numbness<\/li>\n<li>stabbing pain in the rash area<\/li>\n<li>fluid-filled blisters<\/li>\n<\/ul>\n<p>The severity of these symptoms varies by patient. Typically flu-like symptoms present three to five days before the herpes rash, adding stinging and itching to the general feeling of malaise that patients feel. As the rash begins to heal, the flu symptoms also resolve.<\/p>\n<p>It should be noted that herpes zoster is not infectious like the original chickenpox virus; the person with herpes zoster has been carrying the virus typically for years.<\/p>\n<p>The NINDS says that the older you get, the more likely you are to suffer from shingles. For adults aged 60, shingles is 10 times more likely to crop up than in younger adults.<\/p>\n<h3>Chronic Nerve Pain Can Develop<\/h3>\n<figure id=\"attachment_23363\" aria-describedby=\"caption-attachment-23363\" style=\"width: 392px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-23363\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067-1024x683.jpg\" alt=\"\" width=\"392\" height=\"261\" srcset=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067-1024x683.jpg 1024w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067-300x200.jpg 300w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067-768x512.jpg 768w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067-600x400.jpg 600w, https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/bigstock-Close-up-Of-Shingles-Word-With-258153067.jpg 900w\" sizes=\"auto, (max-width: 392px) 100vw, 392px\" \/><\/a><figcaption id=\"caption-attachment-23363\" class=\"wp-caption-text\"><em>A shingles outbreak can leave patients with chronic nerve pain.<\/em><\/figcaption><\/figure>\n<p>Adults that go through a shingles outbreak are at risk of developing chronic nerve pain that can last for years after an outbreak. This pain is called postherpetic neuralgia, which can last for up to three months after the shingles rash has disappeared. The pain can be severe and can lead to depression, insomnia, weight loss, and general disability. Approximately 20 percent of those who suffer from shingles will be plagued with this long-term nerve pain.<\/p>\n<p>There is no cure for shingles currently, but there are two drugs on the market that help make the symptoms less severe when an attack occurs. Antiviral medications are typically used to lessen the severity of the attack. Two of the latest treatments for shingles include acyclovir and Valtrex, medications that are commonly used to fight the herpes virus in all its forms.<\/p>\n<h3>Acyclovir<\/h3>\n<p>Acyclovir is the generic name for Zovirax. Acyclovir is one of the first and most widely used antiviral treatments for the herpes simplex virus, which produces cold sores, and the herpes zoster virus, which presents as shingles. Acyclovir comes in three forms: Intravenous, oral, and topical applications. The intravenous solution is typically used for severely ill patients or those with immune disorders such as HIV\/AIDS.<\/p>\n<p>Acyclovir works to suppress the herpes virus by disrupting its ability to reproduce in the nerve cells. In 1980 the <a href=\"http:\/\/drugtopics.modernmedicine.com\/drug-topics\/content\/tags\/acyclovir\/fda-approves-acyclovir-buccal-tablets-recurrent-herpes-labialis\">Food and Drug Administration (FDA) approved acyclovir<\/a> to treat primary and recurrent episodes of herpes and shingles infections. Scientific studies showed few side effects (less than 1 percent of test subjects experienced any ill effects) from the medication and there are no current drug interactions specified for the drug. Side effects of the medication could include:<\/p>\n<ul>\n<li>diarrhea<\/li>\n<li>hair loss<\/li>\n<li>nausea or vomiting<\/li>\n<li>nervousness<\/li>\n<li>tiredness<\/li>\n<\/ul>\n<p>Patients who are at risk of dehydration or who have kidney problems should not take the drug.<\/p>\n<p><a href=\"https:\/\/www.researchgate.net\/publication\/45288041_Acyclovir_versus_valacyclovir\">Some studies<\/a> have actually shown that acyclovir may also work to repress the virus that causes HIV\/AIDS, but more research needs to be done.<\/p>\n<p>The medication, as prescribed by a doctor, should be given one hour after the emergence of the shingles virus, and the dosage varies from 200 to 800 milligrams to be taken somewhere between three and five times a day.<\/p>\n<h3>Valacyclovir (Valtrex)<\/h3>\n<p>Now let&#8217;s look at valacyclovir, or Valtrex, which is the brand name for this antiviral drug. The FDA approved valacyclovir in 1995. In 2009, the generic version of Valtrex, called valacyclovir, was released.<\/p>\n<p>Like acyclovir, valacyclovir cannot cure herpes, but it can stop the outbreak by attacking and preventing the virus from replication in human nerve cells. According to research studies, valacyclovir appears to be absorbed more quickly, which means it is administered less frequently than acyclovir. Apart from this difference, valacyclovir works in the same manner with the same efficacy as acyclovir.<\/p>\n<p>Like, acyclovir, valacyclovir should be administered quickly after a shingles outbreak. Valacyclovir has been approved for both the genital and facial herpes infections as well as outbreaks of herpes zoster. It can be prescribed for children suffering from chickenpox.<\/p>\n<p>However, valacyclovir works faster than acyclovir to relieve pain, with smaller doses needed. A three-a-day daily dose of 300 to 500 milligrams is typically the prescribed amount.<\/p>\n<p>Another benefit of valacyclovir is that it serves as an alternative to acyclovir if the patient doesn\u2019t respond to a dosing of acyclovir. Valacyclovir may be eliminated completely if the patient responds and is symptom-free for four months.<\/p>\n<p>Like acyclovir, valacyclovir has a low incidence of side effects, however, the patient could experience:<\/p>\n<ul>\n<li>dizziness<\/li>\n<li>headaches<\/li>\n<li>nausea and vomiting<\/li>\n<li>stomach pain<\/li>\n<\/ul>\n<p>Unlike acyclovir, valacyclovir may interact with other drugs, such as IV antibiotics, cancer medications, methotrexate, arthritis medications, and more. Always check with a physician about possible drug interactions as part of your treatment regimen.<\/p>\n<h3>Which is Better?<\/h3>\n<p>While acyclovir is more commonly prescribed, valacyclovir does have a faster effect and also lasts longer than Acyclovir. However, the effectiveness of both drugs is dependent upon how quickly you take them and how severe the outbreak is. Both drugs have similar side effects and work in the same way. However, valcyclovir does have a higher rate of drug interactions, so see your doctor and determine which treatment is best for you.<\/p>\n<h3>Preventing Shingles<\/h3>\n<figure style=\"width: 666px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"https:\/\/www.edrugstore.com\/blog\/wp-content\/uploads\/2018\/01\/acyclovir.jpg\" alt=\"Acyclovir\" width=\"666\" height=\"422\" \/><figcaption class=\"wp-caption-text\"><em>Valacyclovir does have a faster effect and also lasts longer than acyclovir.<\/em><\/figcaption><\/figure>\n<p><em>\u201cOn the whole, your immune system does a remarkable job of defending you against disease-causing microorganisms. But sometimes it fails. . . .\u201d<\/em><\/p>\n<p><a href=\"https:\/\/www.health.harvard.edu\/staying-healthy\/how-to-boost-your-immune-system\">&#8212; Harvard Health Publishing<\/a><\/p>\n<p>Taking steps to prevent a shingles outbreak is important for anyone over the age of 50.<\/p>\n<p>The Zostavax vaccine is currently approved by the FDA for people over the age of 50 years old that have been infected with chickenpox. The drug is currently believed to <a href=\"https:\/\/www.livestrong.com\/article\/216790-flu-symptoms-with-shingles\/\">reduce the risk of a shingles outbreak<\/a> by about 50 percent. However, even if a vaccinated individual does develop shingles, the symptoms are likely to be far less severe than among those who have not been vaccinated.<\/p>\n<p>A publication from <a href=\"https:\/\/www.health.harvard.edu\/staying-healthy\/how-to-boost-your-immune-system\">Harvard Health<\/a> suggests that boosting your immune system can help shore up the body\u2019s natural defenses to prevent everything from a common cold to a shingles outbreak. \u00a0A healthy lifestyle is the first defense toward naturally preventing shingles. This includes:<\/p>\n<ul>\n<li>staying away from tobacco products<\/li>\n<li>eating well<\/li>\n<li>exercising routinely<\/li>\n<li>losing weight<\/li>\n<li>drinking alcohol moderately<\/li>\n<li>getting plenty of sleep<\/li>\n<li>avoiding infections by washing hands frequently<\/li>\n<li>minimizing stress<\/li>\n<\/ul>\n<p>While these are all solid techniques for preventing shingles, if an outbreak occurs the two antivirals acyclovir and valacyclovir will help patients recover more quickly from this debilitating virus.<\/p>\n<p>Both acyclovir and Valtrex, a brand-name formulation of valacyclovir, can be ordered online from longtime online facilitator eDrugstore.com. A prescription is required to order these drugs, but if you don&#8217;t yet have one, eDrugstore can arrange a complimentary online consultation with a licensed U.S. physician who can authorize a prescription if appropriate. To learn more, visit eDrugstore&#8217;s <a href=\"https:\/\/www.edrugstore.com\/sexual-health\/\">Sexual Health page<\/a>.<\/p>\n<p><!-- Media Shower Impressions --><\/p>\n<div class=\"ms_article_id\" style=\"display: none;\" data-ms-article-id=\"64630\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Neither acyclovir nor valacyclovir is a cure for shingles, an outbreak of the varicella-zoster virus in adults. Both, however, can significantly reduce the discomfort and severity of shingles symptoms. Some research indicates that the winter season seems to bring with it a weakening of the body&#8217;s immune system. This, of course, makes you more vulnerable [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10164,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_autoblog_aioseo_focus_keyphrase":"","_autoblog_aioseo_title":"","_autoblog_aioseo_description":"","footnotes":""},"categories":[20],"tags":[23,53],"class_list":["post-10139","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-erectile-dysfunction","tag-erectile-dysfunction-2","tag-valtrex"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Standard treatments for shingles include both Acyclovir and Valtrex. How are these two medications alike and how are they different? 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