Happy woman holding nasal spray

Can Nasonex Nasal Spray Protect You From COVID-19?


  • Nasonex Nasal spray is a popular corticosteroid medication for people with allergies or sinusitis.
  • A 2021 study revealed that nasal corticosteroid sprays reduced the risk of severe COVID-19 complications.
  • However, scientists don’t have enough data yet to recommend the use of nasal corticosteroids for COVID-19 prevention.
  • If you’re already on Nasonex for an existing health condition, stay on it as directed.

A 2021 study revealed that nasal corticosteroid sprays, such as Nasonex, reduce the risk of getting a severe case of COVID-19. Here’s what we know so far about the effects and mechanism of action of those drugs in coronavirus infections. Should you start using them as COVID-19 prevention?

Promising Study on Corticosteroid Steroid Nasal Sprays

COVID-19 is a novel and ever-evolving virus. Scientists are learning new things about it every day. A 2021 research article published in the Journal of Allergy and Clinical Immunology presented an interesting discovery.

The study authors looked at the Cleveland Clinic COVID-19 Research Registry. More than 10,000 people in the database had been using nasal corticosteroids when they were diagnosed with COVID-19.

Those patients demonstrated a lower risk for three serious coronavirus-related complications:

  • Hospitalization 
  • ICU admission
  • In-hospital mortality

The outcomes – although promising – are but a first step in our understanding of the role of steroids in COVID-19. Study authors stated that the analysis had some limitations and that we need more in-depth trials to get the full picture. 

Let’s look at what science already tells us about corticosteroids.

What Are Intranasal Corticosteroids?

Intranasal corticosteroids are a type of anti-inflammatory medication. Your doctor or pharmacist may recommend using them as nose sprays for:

  • Allergic rhinitis
  • Chronic sinusitis
  • Nasal polyps

One of the common products used for those symptoms is Nasonex. This drug contains a steroid called mometasone, and is currently available in the United States by prescription. People usually take it over prolonged periods, as the risk of serious side effects is low.

How Corticosteroids Help in COVID-19?

Because we’re dealing with a new discovery here, we still don’t understand how nasal corticosteroids help coronavirus patients. Scientists suspect it has something to do with virus entry points in our noses. 

Experts are examining the effects on health and a potential life-saving role for corticosteroids. Research is ongoing into the effects of similar inhaled medications that are already being used in COVID-19 treatment. 

For example, some hospitalized coronavirus patients have an increased chance of survival if corticosteroids are included in their treatment. Medical guidelines are regularly updated as new data and study results roll in.

Should You Start Using Nasonex as COVID-19 Prevention?

As medical experts are trying to make sense of coronavirus and ways to protect us from it, it wouldn’t be surprising if you’re confused. Should you start using sprays like Nasonex as a preventive measure? Or maybe it’s a good idea to keep them at home in case you test positive for COVID-19?

The simple answer for now is to wait. We need more clinical trials to confirm that using nasal corticosteroid sprays is beneficial and safe in COVID-19. Starting a long-term preventive treatment with a medication you don’t need is not recommended at this point.

While sprays like Nasonex don’t come with serious side effects, they can cause problems like:

  • Frequent nosebleeds
  • Headaches
  • Cough
  • Sores inside the nose

But what if you’re already using Nasonex to treat a health condition? In that case, stay on it for as long as directed. If you’re tolerating the drug well, don’t switch to another treatment unless necessary. 

Nasal Sprays Could Help Us Fight the Pandemic

Research on corticosteroids in COVID-19 is important because it can help save lives around the world. Vaccination programs are lagging in the developing countries, and the statistics are shocking. According to World Bank representatives, only 1.1 percent of people living in low-income countries received at least one dose of the vaccine.

Corticosteroid nasal sprays could help us beat the pandemic on a global scale. If science confirms their positive impact, people could start using these sprays as prevention or to avoid serious COVID-19 complications.

Be Careful Whose Advice You Follow

Living in a global pandemic makes us anxious. Social media is full of tips from health gurus and celebrities who swear by certain supplements or essential oils to keep them COVID-free.

Tread carefully and double check the facts behind the health advice you follow. If in doubt, ask your doctor or pharmacist.

It’s tempting to believe in a quick solution to the COVID-19 pandemic, but the reality is much more complicated. The best thing to do is follow evidence-based recommendations.

Protect Yourself from COVID-19

Getting vaccinated is still your best protection against coronavirus. And the well-known hygiene recommendations still hold strong:

  • Wear a mask where required and in crowded places. 
  • Avoid handshakes and wash your hands often.
  • If you have COVID-19 symptoms, such as high fever, strong cough, loss of smell and taste, go to the doctor as soon as possible.

eDrugstore Will Keep You Informed

eDrugstore is your source for evidence-based information on men’s health. As more information becomes available about corticosteroids and COVID prevention, we’ll keep you posted. You can also follow our blog.

In the meantime, if you’re struggling with allergies or erectile dysfunction or have other health needs, such as weight loss or smoking cessation, we can help. We offer complimentary online consultations with U.S.-licensed physicians, and virtual health visits and shipping are always free. 

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