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How Long Does Cialis Last?

Cialis can remain effective for up to 36 hours, a fact that gave the drug its designation as “The Weekend Pill.” Individual physiology may cause the drug to remain in the system for shorter or longer periods of time, but regardless, Cialis has a much longer half-life than that of other ED drugs like Viagra and Levitra. 

 

For most men, Cialis starts affecting the body a half-hour to an hour after taking a dose, and the drug typically remains in the system for around 36 hours, on average.  However, there are other factors that can affect how long Cialis stays in your system.

First, it’s important to remember that Cialis is a drug with a long half-life in the body, much longer than other drugs with a similar function.  The “half-life” of a drug is how long it takes for half the drug to leave the body.  Viagra has a half-life of 4 hours, while Cialis has a half-life of 17 hours. That is why the effects of Cialis last longer than Viagra. In addition, there are other factors that can affect how long Cialis remains in the body and how long it remains effective.

Things That Affect Cialis Half-Life in the Body

Most drugs are broken down in the kidneys and liver. If your kidney or liver function is impaired, or you take drugs that inhibit the function of the kidneys or liver, Cialis will stay in your system longer as it is not being broken down. Similarly, Cialis, which works as a vasodilator, may combine with other drugs you are taking which open up the blood vessels and may make the effects last longer.  While this sounds good, it can actually be quite dangerous, because taking multiple vasodilators together can result in a dangerous drop in blood pressure and lead to fainting.

Believe it or not, grapefruit juice, as well as other drugs like cimetidine (an antacid) can result in higher-than-expected blood levels of many drugs. Therefore, it’s inadvisable to take drugs like Cialis with grapefruit juice, or while taking cimetidine.

Finally, Cialis should never be combined with other drugs in its class, such as Viagra (sildenafil) or Levitra (vardenafil).  Taken together, these drugs combine to cause low blood pressure and other side effects, like headaches, vision problems, and indigestion.

Headache is one of the more common Cialis side effects but is usually not severe.

Everyone’s Physiology Is Different

Beyond that, each person has a different reaction to the drug; some users will see effects for a longer period of time, while others have bodies that break Cialis down faster and thus have less of an effect. Cialis’ nickname as “The Weekend Pill” resulted from users who found they could take the drug on a Friday night and still experience relief from ED on Sunday morning. While the drug may be this long-lasting for some men, it’s not the case for everyone.

Be Aware of the Remote Risk for Priapism

Remember, one of the most dangerous side effects of Cialis, as well as other ED drugs, is priapism, or an erection that lasts for more than four hours.  While this may sound appealing, or as a dirty joke, it is actually a medical emergency that can require shunts or even major surgery and is extremely painful to the individual suffering it. If this happens to you, you need to get to the nearest emergency department to avoid long-term or even permanent damage. Fortunately, this condition, priapism, is extremely rare.

When blood stays in the spongy tissues of the penis for too long, the blood will begin to stagnate, causing serious problems in the penis itself.  In severe cases, priapism has forced doctors to perform surgery to save healthy tissue and prevent complications including gangrene.

So, remember, before taking Cialis, check each of the medications you’re already on to ensure there are no negative combinations. Take it only as directed, and if you notice serious side effects like priapism, seek medical attention.

Obtain Cialis with Maximum Convenience

At eDrugstore, we have been providing loyal customers with ED medications like Cialis and Viagra for over 20 years. And now we also offer generic alternatives for both these medications. If you are interested in trying Cialis, Viagra, or any of the other medications approved in the US for treating ED, it’s easy to get started with eDrugstore.com. Working with US-licensed doctors and pharmacists, we provide men with prescription lifestyle medications like Cialis with unmatched convenience, security, and discretion.