Red grocery basket filled with items.

Cialis and Tadalafil Prices at CVS

CVS frequently adjusts its retail price for the erectile dysfunction medications Cialis and tadalafil. Back in January 2020, the prices at CVS for 20 milligrams of both ED prescriptions (Cialis and tadalafil) were lower than at competing retail outlets such as Walgreens, Walmart, and Rite Aid.


In August 2022, CVS prices are slightly higher than most major competitors. The CVS price for 20 milligrams of Cialis was $75.36, and tadalafil 20 milligrams is $18.32

Overall, the average price for 20 milligrams of Cialis in August is $74.16 across major retailers, and tadalafil dropped to $6.82. Price fluidity is one reason that consumers should consider price and other factors when making their decisions between brick-and-mortar retail outlets or convenient online pharmacies such as eDrugstore.com.

About Cialis and Tadalafil

Cialis is the brand name of the drug tadalafil, an erectile dysfunction medication that was approved by the FDA in 2003. The generic version has been available to consumers since October 2018. 

Like other erectile dysfunction medications, Cialis/tadalafil is a vasodilator. This means that the drug helps men achieve and maintain an erection by inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the body. Limiting the production of PDE5 allows more blood to flow to the smooth muscle tissues of the penis, creating a firmer erection.  

Cialis and tadalafil are similar medications to other erectile dysfunction drugs, such as sildenafil (sold as the brand name Viagra) and vardenafil (sold under the brand name Levitra). All three medications are PDE5 inhibitors.

Why Do Men Choose Cialis?

There are several reasons why men and their doctors decide that Cialis is right for them. 

  • It stays in the body longer. Medications such as Viagra only stay in a man’s system for three or four hours. This means that patients must plan their medication and their sexual activity within a limited window of efficacy. Cialis, in contrast, stays in the system for as long as 17-1/2 hours and can be effective in helping men achieve and maintain an erection for 36 hours. For this reason, it’s become known the “weekend drug,” a medication that will help men be ready for sex all weekend. 
  • There are different dosing choices for Cialis. Unlike some other popular ED medications such as Viagra, there are two dosing regimens for Cialis, daily and as-needed. Patients taking daily Cialis are typically prescribed 2.5 milligrams per day, while those taking it as needed may use anywhere between 5 milligrams and 20 milligrams per occasion. Your doctor will consult with you to find the best plan and the proper dosage for you. 
  • There are slight differences in the common side effects. While many of the side effects of vasodilators are similar, some patients and their physicians will choose Cialis over Viagra because Cialis does not have the reported side effect of vision changes some men experience with Viagra. 

CVS and Other Retail Pharmacies: Where Should You Buy Cialis?

If you have been prescribed Cialis or tadalafil, your next choice will be where to buy. CVS is the largest retail pharmacy with physical locations in the United States, dispensing $109 billion in revenue in the 2019 fiscal year. CVS is closely followed by Walgreens ($84.3 billion) and Walmart ($21.2 billion). Rite Aid is another player in the prescription market, having dispensed $14 billion in revenue in 2019.

Many men will make the decision of where to buy based on price. The prices for Cialis and tadalafil are fluid and change from month to month. Especially in the case of the generic tadalafil, major retailers spend a lot of time seeking a “Goldilocks” price for the medication. Each outlet seeks to balance price with profit and customer satisfaction. This can mean, however, that men run into a surprise when they pick up their prescription every month. 

Benefits of Online Pharmacies Like eDrugstore

There are multiple benefits to ordering from an online pharmacy like eDrugstore. Ordering online allows you to quickly and easily order refills, renew prescriptions, check your order status, view your claims history, and find prescription drug information.

In addition, if you don’t yet have a prescription, eDrugstore will set you up with a complimentary online consultation with a licensed U.S. doctor, who will go through your medical history with you and recommend both the ED medication and the dosing regimen that will work best for you. This service provides huge savings in money and time as well as more privacy.

Using eDrugstore will save you time in a variety of ways (and as the saying goes, time is money!). When you use eDrugstore, you save time by:

  • Ordering prescriptions and refills
  • Not having to drive to a retail store
  • Not having to wait in line
  • Being able to access your prescription records for tax purposes and for HSAs and FSAs
  • Having access to easy information about your prescription

Many people don’t enjoy the hassle or the time lost in going to a brick-and-mortar drugstore. Savvy consumers choose convenience, discretion, and savings of time and money when they choose to shop online or get, fill, and refill their prescriptions online.

Check Out the Services That eDrugstore Has to Offer

Whether or not you already have a prescription for ED medication, eDrugstore is here to help. Whether you choose to speak to us via phone or online, we will provide you with only the best in medical consultation, information, and support.

Browse our medication guide to find the right ED medication for you and arrange your free medical consultation today. With eDrugstore, virtual health visits and shipping are always free. 

20 Pill Generic Viagra Offer