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Average Cost of Cialis Is $9.55; Click for More

While Cialis won't cure impotence, it does allow men with erection problems to overcome them temporarily.

While Cialis won’t cure impotence, it does allow men with erection problems to overcome them temporarily.

If you’re experiencing persistent symptoms of impotence and have been unable to find relief through lifestyle modifications, it may be time to try one of the popular impotence medications to see if it can help you regain normal erectile function, at least temporarily.

While there are a number of drugs from which to choose, Cialis is one of the more popular brands and one of the more versatile because it is available in two distinct formulations.

Cialis for Daily Use

The first, known as Cialis for Daily Use, is the most reasonably priced. And if like the Boy Scouts, you obsess about being prepared, it probably is the drug of choice for you. As its name suggests, the medication is taken daily. The drug’s manufacturer claims that it allows you to get and keep an erection whenever the time is right, eliminating the need to pop a pill 30 minutes to an hour before sexual activity when the mood turns romantic.

The average cost of Cialis for Daily Use is $9.55 per tablet if you order a 60-day supply from eDrugstore.com for a total price of $573. If you’d prefer to buy only 30 pills — a month’s supply — you’ll pay $10.20 per tablet. For the greatest savings, order a 90-day supply for $810, which lowers your price per pill to $9.00. Cialis for Daily Use is available only in 5-milligram tablets.

Cialis for Use as Needed

The second formulation of Cialis is actually the version of the drug that was originally introduced by Eli Lilly & Company in late 2003. Marketed today as Cialis for Use as Needed, to distinguish it from the formulation taken daily, this form of the drug is sometimes known as the ¨weekend pill¨ because of its long-lasting effects. Effective for up to 36 hours, Cialis for Use as Needed can be taken at 8 or 9 p.m. on a Friday night and remain effective until 8 or 9 o’clock Sunday morning, according to the drug’s manufacturer.

The recommended starting dose for Cialis for Use as Needed is 10 milligrams, which works for most men. However, if 10 milligrams is not enough to get the job done, the dose can be increased to 20 milligrams. In the unlikely event that 10 milligrams is more than you need to get the desired effects, your doctor can lower the dose to 5 milligrams.

Longest-Lasting Impotence Drug

Cialis is produced and marketed in the United States by Eli Lilly & Company, the world headquarters of which is seen above.

Cialis is produced and marketed in the United States by Eli Lilly & Company, the world headquarters of which is seen above.

No other single-dose impotence drug currently on the market offers the long-lasting effects of Cialis for Use as Needed, which helps to explain its hefty price tag. The average cost of a 10-milligram dose of Cialis for Use as Needed is $24.75, which you can get if you order 10 20-milligram tablets of the medication from eDrugstore.com for a total price of $495. All first orders of impotence drugs from eDrugstore come with a free pill-splitter that will allow you to convert those 20-milligram pills into 20 10-milligram doses.

To increase your savings when ordering Cialis for Use as Needed, bump up your order to 20 20-milligram pills for a total of $969. When split, this order yields 40 10-milligram doses, lowering your cost per 10-milligram dose to roughly $24.23.

The active ingredient in both formulations of Cialis is tadalafil, a member of the family of impotence drugs known as PDE5 inhibitors. Other drugs in this family include Viagra (sildenafil citrate), Levitra and Staxyn (vardenafil hydrochloride), and Stendra (avanafil). While all of these drugs work in much the same way, each varies from the others somewhat in chemical structure. You may find that all of these drugs work for you with virtually no difference from one to another. However, another man may find that while all of the drugs eventually produce the desired result, one seems to work better than the others and has fewer, if any, side effects.

How These Drugs Work

Collectively, these drugs are known as PDE5 inhibitors because they temporarily inhibit an enzyme known as phosphodiesterase-5, which can throw a monkey wrench into the erectile process for men who are already suffering diminished blood flow to the penis.

While impotence can stem from both physiological and psychological causes, the vast majority of erection problems fall into the former category and are traceable to compromised blood flow. The PDE5 inhibitors are unlikely to be of great help to men whose impotence is caused by depression or other psychological issues.

Cialis and other PDE5 inhibitors have helped millions of men to resume relatively normal sex lives.

Cialis and other PDE5 inhibitors have helped millions of men to resume relatively normal sex lives.

Cialis and the other PDE5 inhibitors work their magic by disabling the PDE5 enzyme. To understand why that’s important, we need to look a little more closely at the erectile process, which begins in the brain with feelings of sexual arousal. Once the brain detects these signs of sexual desire, it triggers a release of nitric oxide in the pelvic region. The nitric oxide sets off secondary chemical reactions, one of which creates a chemical substance called cyclic guanosine monophosphate, or cGMP.

Strong Blood Flow Essential

No erection is possible without strong blood flow into the penis, which cGMP facilitates by relaxing the smooth muscles that line the arteries that supply the penis. As these muscles relax, the arteries dilate and the flow of blood into the penis increases, filling the spongy erectile tissue of the penis and creating an erection.

Here’s where the PDE5 inhibitors become important. One of the primary functions of the PDE5 enzyme — which these drugs temporarily deactivate — is the breakdown of cGMP. Left to do its own thing, the PDE5 enzyme could easily break down the cGMP facilitating an erection before it has completed its tasks. By holding the PDE5 enzyme at bay for four to 36 hours, the impotence drugs optimize blood flow in the pelvic region and make it easier for men taking the drugs to get and keep an erection strong enough for intercourse.

Both formulations of Cialis, as well as the other PDE5 inhibitors, have been subjected to rigorous clinical testing, which has shown these medications to be safe and effective for most men. However, you should never take one of these drugs before consulting a medical professional who can review your medical history to make sure that you suffer from no conditions that would contraindicate the use of these drugs.

Incompatible with Nitrates

Cialis should not be taken if you are currently taking nitrate-based drugs for the treatment of angina. Both medications lower blood pressure and taken together could cause a potentially life-threatening drop in blood pressure.

The most common side effects of Cialis are mild and generally disappear altogether upon continued use of the drug. These side effects include back pain, digestive upset, facial flushing, headache, muscle soreness, and nasal congestion.

In addition to its dangerous interaction with nitrate-based drugs, Cialis can have adverse but less dangerous interactions with other medications, including some antibiotics, antidepressants, antihistamines, and blood pressure medications. If you are taking a drug that interacts adversely with Cialis, consult your doctor to see if you can be switched to an alternate medication that doesn’t have the same negative effects.

Don Amerman is a freelance author who writes extensively about a wide array of nutrition and health-related topics.

Don Amerman has spent more than three decades in the business of writing and editing. During the last 15 years, his focus has been on freelance writing. For almost all of his writing, He has done all of his own research, both online and off, including telephone and face-to-face interviews where possible. Don Amerman on Google+